What is the catalog number for FGF1 Antibody?

The catalog number for FGF1 Antibody is OACA06749-100UL.

What sizes are available for FGF1 Antibody?

FGF1 Antibody is available in the following size(s): 100 µL.

Is FGF1 Antibody in stock?

FGF1 Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

FGF1 Antibody

Product Specifications

CAS Number

9007-83-4

Gene Name

Fibroblast growth factor 1

Gene Aliases

Acidic fibroblast growth factor; AFGF; beta-endothelial cell growth factor; ECGF; ECGFA; ECGFB; ECGF-beta; Endothelial cell growth factor; endothelial cell growth factor, alpha; endothelial cell growth factor, beta; FGF-1; FGFA; FGF-alpha; fibroblast growth factor 1; fibroblast growth factor 1 (acidic) ; GLIO703; HBGF1; HBGF-1; heparin-binding growth factor 1.

Gene ID

2246

Accession Number

NP_000791

Reactivity

Human

Immunogen

Recombinant Human Fibroblast growth factor 1 protein (16-155AA)

Target

Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrin ITGAV:ITGB3. Its binding to integrin, subsequent ternary complex formation with integrin and FGFR1, and the recruitment of PTPN11 to the complex are essential for FGF1 signaling. Induces the phosphorylation and activation of FGFR1, FRS2, MAPK3/ERK1, MAPK1/ERK2 and AKT1 (PubMed:18441324, PubMed:20422052) . Can induce angiogenesis (PubMed:23469107) .

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Polyclonal Antibody

Applications

Enzyme-linked immunosorbent assay|Immunofluorescence|Immunohistochemistry

Purification

Affinity Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol