SLURP1 Antibody
Product Specifications
CAS Number
9007-83-4
Gene Name
Secreted LY6/PLAUR domain containing 1
Gene Aliases
Anti-neoplastic urinary protein; ANUP; ARS; ARS component B; ARS (component B) -81/S; ArsB; LY6LS; LY6-MT; lymphocyte antigen 6-like secreted; MDM; secreted Ly6/uPAR related protein 1; secreted Ly-6/uPAR-related protein 1; SLURP-1.
Gene ID
57152
Accession Number
NP_065160
Reactivity
Human
Immunogen
Recombinant Human Secreted Ly-6/uPAR-related protein 1 protein (1-103AA)
Target
Has an antitumor activity (PubMed:8742060) . Was found to be a marker of late differentiation of the skin. Implicated in maintaining the physiological and structural integrity of the keratinocyte layers of the skin (PubMed:14721776, PubMed:17008884) . In vitro down-regulates keratinocyte proliferation; the function may involve the proposed role as modulator of nicotinic acetylcholine receptors (nAChRs) activity. In vitro inhibits alpha-7-dependent nAChR currents in an allosteric manner (PubMed:14506129, PubMed:26905431) . In T cells may be involved in regulation of intracellular Ca (2+) signaling (PubMed:17286989) . Seems to have a immunomodulatory function in the cornea (By similarity) . The function may implicate a possible role as a scavenger receptor for PLAU thereby blocking PLAU-dependent functions of PLAUR such as in cell migration and proliferation (PubMed:25168896) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
Enzyme-linked immunosorbent assay|Immunohistochemistry
Purification
Affinity Purified
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions
Reconstitution & Storage Instructions
Western Blotting/Immunoblotting (WB/IB) Protocol
Western Blotting/Immunoblotting (WB/IB) Protocol
Immunohistochemistry (IHC) Protocol
Immunohistochemistry (IHC) Protocol
Immunocytochemistry (ICC) Protocol
Immunocytochemistry (ICC) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Blocking Peptide Competition Protocol (BPCP)
Blocking Peptide Competition Protocol (BPCP)
Immunoprecipitation (IP) Protocol
Immunoprecipitation (IP) Protocol
Antibody Array (AA) Protocol
Antibody Array (AA) Protocol
Format
Liquid
Reconstitution
-20°C or -80°C
Fragment
IgG
NCBI Gene Symbol
SLURP1
Host or Source
Rabbit
Protein Name
Secreted Ly-6/uPAR-related protein 1
Gene Name URL
SLURP1
Nucleotide Accession Number
NM_020427
Frequently Asked Questions
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