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HIP1 Antibody

Product Specifications

CAS Number

9007-83-4

Gene Name

Huntingtin interacting protein 1

Gene Aliases

HIP-I; huntingtin-interacting protein 1; huntingtin-interacting protein I; ILWEQ; SHON; SHONbeta; SHONgamma.

Gene ID

3092

Accession Number

NP_001230127

Reactivity

Human

Immunogen

Recombinant Human Huntingtin-interacting protein 1 protein (410-690AA)

Target

Plays a role in clathrin-mediated endocytosis and trafficking (PubMed:11532990, PubMed:11577110, PubMed:11889126) . Involved in regulating AMPA receptor trafficking in the central nervous system in an NMDA-dependent manner (By similarity) . Regulates presynaptic nerve terminal activity (By similarity) . Enhances androgen receptor (AR) -mediated transcription (PubMed:16027218) . May act as a proapoptotic protein that induces cell death by acting through the intrinsic apoptosis pathway (PubMed:11007801) . Binds 3-phosphoinositides (via ENTH domain) (PubMed:14732715) . May act through the ENTH domain to promote cell survival by stabilizing receptor tyrosine kinases following ligand-induced endocytosis (PubMed:14732715) . May play a functional role in the cell filament networks (PubMed:18790740) . May be required for differentiation, proliferation, and/or survival of somatic and germline progenitors (PubMed:11007801, PubMed:12163454) .

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Polyclonal Antibody

Applications

Enzyme-linked immunosorbent assay|Immunohistochemistry|Western blot

Purification

Affinity Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Format

Liquid

Reconstitution

-20°C or -80°C

Fragment

IgG

NCBI Gene Symbol

HIP1

Host or Source

Rabbit

Protein Name

Huntingtin-interacting protein 1

Gene Name URL

HIP1

Nucleotide Accession Number

NM_001243198

Frequently Asked Questions

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