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TPRKB Antibody

Product Specifications

CAS Number

9007-83-4

Gene Name

TP53RK binding protein

Gene Aliases

CGI121; CGI-121; EKC/KEOPS complex subunit TPRKB; GAMOS5; PRPK (p53-related protein kinase) -binding protein; PRPK-binding protein; TP53RK-binding protein.

Gene ID

51002

Accession Number

NP_001317315

Reactivity

Human

Immunogen

Recombinant Human EKC/KEOPS complex subunit TPRKB protein (1-175AA)

Target

Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t (6) A37) in tRNAs that read codons beginning with adenine (PubMed:22912744, PubMed:28805828) . The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37 (PubMed:22912744, PubMed:28805828) . TPRKB acts as an allosteric effector that regulates the t (6) A activity of the complex. TPRKB is not required for tRNA modification (PubMed:22912744, PubMed:28805828) .

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Polyclonal Antibody

Applications

Enzyme-linked immunosorbent assay|Immunohistochemistry|Western blot

Purification

Protein G Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Format

Liquid

Reconstitution

-20°C or -80°C

Fragment

IgG

NCBI Gene Symbol

TPRKB

Host or Source

Rabbit

Protein Name

EKC/KEOPS complex subunit TPRKB

Gene Name URL

TPRKB

Nucleotide Accession Number

NM_001330386

Frequently Asked Questions

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