TPRKB Antibody
Product Specifications
CAS Number
9007-83-4
Gene Name
TP53RK binding protein
Gene Aliases
CGI121; CGI-121; EKC/KEOPS complex subunit TPRKB; GAMOS5; PRPK (p53-related protein kinase) -binding protein; PRPK-binding protein; TP53RK-binding protein.
Gene ID
51002
Accession Number
NP_001317315
Reactivity
Human
Immunogen
Recombinant Human EKC/KEOPS complex subunit TPRKB protein (1-175AA)
Target
Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t (6) A37) in tRNAs that read codons beginning with adenine (PubMed:22912744, PubMed:28805828) . The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37 (PubMed:22912744, PubMed:28805828) . TPRKB acts as an allosteric effector that regulates the t (6) A activity of the complex. TPRKB is not required for tRNA modification (PubMed:22912744, PubMed:28805828) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
Enzyme-linked immunosorbent assay|Immunohistochemistry|Western blot
Purification
Protein G Purified
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions
Reconstitution & Storage Instructions
Western Blotting/Immunoblotting (WB/IB) Protocol
Western Blotting/Immunoblotting (WB/IB) Protocol
Immunohistochemistry (IHC) Protocol
Immunohistochemistry (IHC) Protocol
Immunocytochemistry (ICC) Protocol
Immunocytochemistry (ICC) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Blocking Peptide Competition Protocol (BPCP)
Blocking Peptide Competition Protocol (BPCP)
Immunoprecipitation (IP) Protocol
Immunoprecipitation (IP) Protocol
Antibody Array (AA) Protocol
Antibody Array (AA) Protocol
Format
Liquid
Reconstitution
-20°C or -80°C
Fragment
IgG
NCBI Gene Symbol
TPRKB
Host or Source
Rabbit
Protein Name
EKC/KEOPS complex subunit TPRKB
Gene Name URL
TPRKB
Nucleotide Accession Number
NM_001330386
Frequently Asked Questions
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