NUP85 Antibody
Product Specifications
Gene Name
Nucleoporin 85
Gene Aliases
85 kDa nucleoporin; FROUNT; NPHS17; nuclear pore complex protein Nup85; nucleoporin 85kDa; nucleoporin Nup75; nucleoporin Nup85; Nup75; Pericentrin-1.
Gene ID
79902
Accession Number
NP_001290205
Reactivity
Human|Mouse
Immunogen
Recombinant Human Nuclear pore complex protein Nup85 protein (201-500AA)
Target
Essential component of the nuclear pore complex (NPC) that seems to be required for NPC assembly and maintenance (PubMed:12718872) . As part of the NPC Nup107-160 subcomplex plays a role in RNA export and in tethering NUP96/Nup98 and NUP153 to the nucleus (PubMed:12718872) . The Nup107-160 complex seems to be required for spindle assembly during mitosis (PubMed:16807356) . NUP85 is required for membrane clustering of CCL2-activated CCR2 (PubMed:15995708) . Seems to be involved in CCR2-mediated chemotaxis of monocytes and may link activated CCR2 to the phosphatidyl-inositol 3-kinase-Rac-lammellipodium protrusion cascade (PubMed:15995708) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
Enzyme-linked immunosorbent assay|Immunofluorescence|Immunohistochemistry|Western blot
Purification
Protein G Purified
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions
Reconstitution & Storage Instructions
Western Blotting/Immunoblotting (WB/IB) Protocol
Western Blotting/Immunoblotting (WB/IB) Protocol
Immunohistochemistry (IHC) Protocol
Immunohistochemistry (IHC) Protocol
Immunocytochemistry (ICC) Protocol
Immunocytochemistry (ICC) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Blocking Peptide Competition Protocol (BPCP)
Blocking Peptide Competition Protocol (BPCP)
Immunoprecipitation (IP) Protocol
Immunoprecipitation (IP) Protocol
Antibody Array (AA) Protocol
Antibody Array (AA) Protocol
Format
Liquid
Reconstitution
-20°C or -80°C
Fragment
IgG
NCBI Gene Symbol
NUP85
Host or Source
Rabbit
Protein Name
Nuclear pore complex protein Nup85
Gene Name URL
NUP85
CAS Number
9007-83-4
Nucleotide Accession Number
NM_001303276
Curated Selection
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