MCUB Antibody
Product Specifications
Gene Name
Mitochondrial calcium uniporter dominant negative subunit beta
Gene Aliases
Calcium uniporter regulatory subunit MCUb, mitochondrial; CCDC109B; coiled-coil domain containing 109B; coiled-coil domain-containing protein 109B; mitochondrial calcium uniporter dominant negative beta subunit; mitochondrial calcium uniporter regulatory subunit MCUb.
Gene ID
55013
Accession Number
NP_060388
Reactivity
Human
Immunogen
Recombinant Human Calcium uniporter regulatory subunit MCUb, mitochondrial protein (89-219AA)
Target
Negatively regulates the activity of MCU, the mitochondrial inner membrane calcium uniporter, and thereby modulates calcium uptake into the mitochondrion. Does not form functional calcium channels by itself. Mitochondrial calcium homeostasis plays key roles in cellular physiology and regulates cell bioenergetics, cytoplasmic calcium signals and activation of cell death pathways.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
Enzyme-linked immunosorbent assay|Immunofluorescence|Immunohistochemistry
Purification
Affinity Purified
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions
Reconstitution & Storage Instructions
Western Blotting/Immunoblotting (WB/IB) Protocol
Western Blotting/Immunoblotting (WB/IB) Protocol
Immunohistochemistry (IHC) Protocol
Immunohistochemistry (IHC) Protocol
Immunocytochemistry (ICC) Protocol
Immunocytochemistry (ICC) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Blocking Peptide Competition Protocol (BPCP)
Blocking Peptide Competition Protocol (BPCP)
Immunoprecipitation (IP) Protocol
Immunoprecipitation (IP) Protocol
Antibody Array (AA) Protocol
Antibody Array (AA) Protocol
Format
Liquid
Reconstitution
-20°C or -80°C
Fragment
IgG
NCBI Gene Symbol
MCUB
Host or Source
Rabbit
Protein Name
Calcium uniporter regulatory subunit MCUb, mitochondrial
Gene Name URL
MCUB
CAS Number
9007-83-4
Nucleotide Accession Number
NM_017918
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