P-APMSF (hydrochloride)

P-APMSF is an irreversible inhibitor of serinase. p-APMSF has substrate specificity for positively charged side chains of amino acids, lysine, or arginine. p-APMSF can be used to study the irreversible inhibition of trypsin and thrombin [1].

Product Specifications

CAS Number

[74938-88-8]

Product Name Alternative

P-Amidinophenylmethylsulfonylfluoride (hydrochloride)

UNSPSC

12352005

Hazard Statement

H314

Target

Thrombin

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/p-apmsf-hydrochloride.html

Purity

95.0

Solubility

10 mM in DMSO

Smiles

O=S(CC1=CC=C(C(N)=N)C=C1)(F)=O.[H]Cl

Molecular Formula

C8H10ClFN2O2S

Molecular Weight

252.69

Precautions

H314

References & Citations

[1]Laura R, et al. (p-Amidinophenyl) methanesulfonyl fluoride, an irreversible inhibitor of serine proteases. Biochemistry. 1980 Oct 14;19 (21) :4859-64.