SMG6 Antibody
Product Specifications
CAS Number
9007-83-4
Gene Name
SMG6 nonsense mediated mRNA decay factor
Gene Aliases
C17orf31; EST1 telomerase component homolog A; EST1A; EST1-like protein A; ever shorter telomeres 1A; hSMG5/7a; SMG-6; Smg-6 homolog; smg-6 homolog, nonsense mediated mRNA decay factor; telomerase subunit EST1A; telomerase-binding protein EST1A.
Gene ID
23293
Accession Number
NP_001243756
Reactivity
Human
Immunogen
Recombinant Human Telomerase-binding protein EST1A protein (251-511AA)
Target
Component of the telomerase ribonucleoprotein (RNP) complex that is essential for the replication of chromosome termini. May have a general role in telomere regulation. Promotes in vitro the ability of TERT to elongate telomeres. Overexpression induces telomere uncapping, chromosomal end-to-end fusions (telomeric DNA persists at the fusion points) and did not perturb TRF2 telomeric localization. Binds to the single-stranded 5'- (GTGTGG) (4) GTGT-3' telomeric DNA, but not to a telomerase RNA template component (TER) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
Enzyme-linked immunosorbent assay|Immunofluorescence|Immunohistochemistry
Purification
Protein G Purified
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions
Reconstitution & Storage Instructions
Western Blotting/Immunoblotting (WB/IB) Protocol
Western Blotting/Immunoblotting (WB/IB) Protocol
Immunohistochemistry (IHC) Protocol
Immunohistochemistry (IHC) Protocol
Immunocytochemistry (ICC) Protocol
Immunocytochemistry (ICC) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Blocking Peptide Competition Protocol (BPCP)
Blocking Peptide Competition Protocol (BPCP)
Immunoprecipitation (IP) Protocol
Immunoprecipitation (IP) Protocol
Antibody Array (AA) Protocol
Antibody Array (AA) Protocol
Format
Liquid
Reconstitution
-20°C or -80°C
Fragment
IgG
NCBI Gene Symbol
SMG6
Host or Source
Rabbit
Protein Name
Telomerase-binding protein EST1A
Gene Name URL
SMG6
Nucleotide Accession Number
NM_001256827
Curated Selection
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