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FbpA Antibody - HRP Conjugated

Product Specifications

CAS Number

9007-83-4

Gene Name

Diacylglycerol acyltransferase/mycolyltransferase Ag85A

Gene Aliases

85A; Acyl-CoA:diacylglycerol acyltransferase; Antigen 85 complex A; diacylglycerol acyltransferase/mycolyltransferase Ag85A; Fibronectin-binding protein A; mpt44; Rv3804c.

Gene ID

886132

Accession Number

NP_857471.1WP_003900759.1

Reactivity

Mycobacterium tuberculosis

Immunogen

Recombinant Mycobacterium tuberculosis Diacylglycerol acyltransferase/mycolyltransferase Ag85A protein (53-331AA)

Target

The antigen 85 proteins (FbpA, FbpB, FbpC) are responsible for the high affinity of mycobacteria for fibronectin, a large adhesive glycoprotein, which facilitates the attachment of M.tuberculosis to murine alveolar macrophages (AMs) . They also help to maintain the integrity of the cell wall by catalyzing the transfer of mycolic acids to cell wall arabinogalactan, and through the synthesis of alpha, alpha-trehalose dimycolate (TDM, cord factor) . They catalyze the transfer of a mycoloyl residue from one molecule of alpha, alpha-trehalose monomycolate (TMM) to another TMM, leading to the formation of TDM. FbpA mediates triacylglycerol (TAG) formation with long-chain acyl-CoA as the acyl donor and 1,2-dipalmitoyl-sn-glycerol (1,2-dipalmitin) as the acyl acceptor. It has a preference for C26:0-CoA over C18:1-CoA.

Clonality

Polyclonal

Conjugation

HRP

Type

Polyclonal Antibody

Applications

Enzyme-linked immunosorbent assay

Purification

Protein G Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Format

Liquid

Buffer

Preservative: 0.03% Proclin 300Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Reconstitution

-20°C or -80°C

Fragment

IgG

NCBI Gene Symbol

FbpA

Host or Source

Rabbit

Protein Name

Diacylglycerol acyltransferase/mycolyltransferase Ag85A

Gene Name URL

FbpA

Nucleotide Accession Number

NC_002945.3

Frequently Asked Questions

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