L1 Antibody - HRP Conjugated
Product Specifications
CAS Number
9007-83-4
Gene Name
Major capsid L1 protein
Gene Aliases
HpV18gp8; major capsid L1 protein.
Gene ID
1489090
Accession Number
NP_040317.1
Reactivity
Human Papillomavirus Type 18
Immunogen
Recombinant HPV18 Major capsid protein L1 protein (1-568AA)
Target
Forms an icosahedral capsid with a T=7 symmetry and a 50 nm diameter. The capsid is composed of 72 pentamers linked to each other by disulfide bonds and associated with L2 proteins. Binds to heparan sulfate proteoglycans on cell surface of basal layer keratinocytes to provide initial virion attachment. This binding mediates a conformational change in the virus capsid that facilitates efficient infection. The virion enters the host cell via endocytosis. During virus trafficking, L1 protein dissociates from the viral DNA and the genomic DNA is released to the host nucleus. The virion assembly takes place within the cell nucleus. Encapsulates the genomic DNA together with protein L2.
Clonality
Polyclonal
Conjugation
HRP
Type
Polyclonal Antibody
Applications
Enzyme-linked immunosorbent assay
Purification
Protein G Purified
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions
Reconstitution & Storage Instructions
Western Blotting/Immunoblotting (WB/IB) Protocol
Western Blotting/Immunoblotting (WB/IB) Protocol
Immunohistochemistry (IHC) Protocol
Immunohistochemistry (IHC) Protocol
Immunocytochemistry (ICC) Protocol
Immunocytochemistry (ICC) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Blocking Peptide Competition Protocol (BPCP)
Blocking Peptide Competition Protocol (BPCP)
Immunoprecipitation (IP) Protocol
Immunoprecipitation (IP) Protocol
Antibody Array (AA) Protocol
Antibody Array (AA) Protocol
Concentration
Varies by lot. See vial for concentration.
Format
Liquid// 0.01M PBS (pH 7.4) with 0.03% Proclin300 and 50% glycerol
Buffer
Preservative: 0.03% Proclin 300Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Reconstitution
Upon receipt, store at -20° C or -80° C. Avoid repeated freeze/thaw cycles.
Fragment
IgG
NCBI Gene Symbol
L1
Host or Source
Rabbit
Protein Name
Major capsid protein L1
Gene Name URL
L1
Nucleotide Accession Number
NC_001357.1
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