PPP1R11 Antibody - HRP Conjugated

Product Specifications

CAS Number

9007-83-4

Gene Name

Protein phosphatase 1 regulatory inhibitor subunit 11

Gene Aliases

CFAP255; E3 ubiquitin-protein ligase PPP1R11; HCG V; HCGV; HCG-V; hemochromatosis candidate gene V protein; inhibitor-3; IPP3; protein phosphatase 1 regulatory subunit 11; protein phosphatase inhibitor 3; t-complex-associated-testis-expressed 5; TCTE5; TCTEX5.

Gene ID

6992

Accession Number

NP_068778.1

Reactivity

Human

Immunogen

Recombinant Human E3 ubiquitin-protein ligase PPP1R11 protein (1-126AA)

Target

Atypical E3 ubiquitin-protein ligase which ubiquitinates TLR2 at 'Lys-754' leading to its degradation by the proteasome. Plays a role in regulating inflammatory cytokine release and gram-positive bacterial clearance by functioning, in part, through the ubiquitination and degradation of TLR2 (PubMed:27805901) . Inhibitor of protein phosphatase 1 (PubMed:9843442) .

Clonality

Polyclonal

Conjugation

HRP

Type

Polyclonal Antibody

Applications

Enzyme-linked immunosorbent assay

Purification

Protein G Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol