PPP1R11 Antibody - HRP Conjugated
Product Specifications
Gene Name
Protein phosphatase 1 regulatory inhibitor subunit 11
Gene Aliases
CFAP255; E3 ubiquitin-protein ligase PPP1R11; HCG V; HCGV; HCG-V; hemochromatosis candidate gene V protein; inhibitor-3; IPP3; protein phosphatase 1 regulatory subunit 11; protein phosphatase inhibitor 3; t-complex-associated-testis-expressed 5; TCTE5; TCTEX5.
Gene ID
6992
Accession Number
NP_068778.1
Reactivity
Human
Immunogen
Recombinant Human E3 ubiquitin-protein ligase PPP1R11 protein (1-126AA)
Target
Atypical E3 ubiquitin-protein ligase which ubiquitinates TLR2 at 'Lys-754' leading to its degradation by the proteasome. Plays a role in regulating inflammatory cytokine release and gram-positive bacterial clearance by functioning, in part, through the ubiquitination and degradation of TLR2 (PubMed:27805901) . Inhibitor of protein phosphatase 1 (PubMed:9843442) .
Clonality
Polyclonal
Conjugation
HRP
Type
Polyclonal Antibody
Applications
Enzyme-linked immunosorbent assay
Purification
Protein G Purified
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions
Reconstitution & Storage Instructions
Western Blotting/Immunoblotting (WB/IB) Protocol
Western Blotting/Immunoblotting (WB/IB) Protocol
Immunohistochemistry (IHC) Protocol
Immunohistochemistry (IHC) Protocol
Immunocytochemistry (ICC) Protocol
Immunocytochemistry (ICC) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Blocking Peptide Competition Protocol (BPCP)
Blocking Peptide Competition Protocol (BPCP)
Immunoprecipitation (IP) Protocol
Immunoprecipitation (IP) Protocol
Antibody Array (AA) Protocol
Antibody Array (AA) Protocol
Format
Liquid
Buffer
PBS
Reconstitution
-20°C or -80°C
Fragment
IgG
NCBI Gene Symbol
PPP1R11
Host or Source
Rabbit
Protein Name
E3 ubiquitin-protein ligase PPP1R11
Gene Name URL
PPP1R11
CAS Number
9007-83-4
Nucleotide Accession Number
NM_021959.2
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