What is the catalog number for ABCB4 Antibody - HRP Conjugated?

The catalog number for ABCB4 Antibody - HRP Conjugated is OACA00083-100UG.

What sizes are available for ABCB4 Antibody - HRP Conjugated?

ABCB4 Antibody - HRP Conjugated is available in the following size(s): 100 µg.

Is ABCB4 Antibody - HRP Conjugated in stock?

ABCB4 Antibody - HRP Conjugated is currently made to order / not held in immediate stock. Contact us for lead time.

Can I return this product if I ordered the wrong one?

As a consumer, you have a 14-day right of withdrawal from receipt under EU consumer protection law, submitted via our withdrawal/cancellation request form. Note this applies to unused, undamaged products, and doesn’t override the expiry/storage conditions on performance-based claims.

Is this product tested for endotoxin levels?

Endotoxin testing status is noted on the datasheet where applicable, particularly for recombinant proteins intended for cell-based or functional assays. If this isn’t listed and you need confirmation, contact support with the catalogue number.

Can I request additional validation data, such as western blot images, for this product?

Additional data may be available on request. Contact our technical support team with the catalogue number and we’ll check what supporting documentation the supplier can provide.

ABCB4 Antibody - HRP Conjugated

Product Specifications

CAS Number

9007-83-4

Gene Name

ATP-binding cassette, sub-family B (MDR/TAP), member 4

Gene Aliases

ATP-binding cassette sub-family B member 4; Mdr; mdr-; mdr-2; Mdr2; multidrug resistance protein 2; multidrug resistance protein 3; P glycoprotein 2; P-glycoprotein 2; P-glycoprotein 3; Pgy; Pgy-; Pgy2; Pgy-2; phosphatidylcholine translocator ABCB4.

Gene ID

18670

Accession Number

NP_000434.1NP_061337.1NP_061338.1

Reactivity

Mouse

Immunogen

Recombinant Mouse Phosphatidylcholine translocator ABCB4 protein (352-708AA)

Target

Energy-dependent phospholipid efflux translocator that acts as a positive regulator of biliary lipid secretion. Functions as a floppase that translocates specifically phosphatidylcholine (PC) from the inner to the outer leaflet of the canalicular membrane bilayer into the canaliculi between hepatocytes. Translocation of PC makes the biliary phospholipids available for extraction into the canaliculi lumen by bile salt mixed micelles and therefore protects the biliary tree from the detergent activity of bile salts (PubMed:8106172, PubMed:7912658, PubMed:7592705, PubMed:7814632, PubMed:8725158, PubMed:9366571) . Plays a role in the recruitment of phosphatidylcholine (PC), phosphatidylethanolamine (PE) and sphingomyelin (SM) molecules to nonraft membranes and to further enrichment of SM and cholesterol in raft membranes in hepatocytes (By similarity) . Required for proper phospholipid bile formation (PubMed:8106172) . Indirectly involved in cholesterol efflux activity from hepatocytes into the canalicular lumen in the presence of bile salts in an ATP-dependent manner (PubMed:7814632, PubMed:8725158) . May promote biliary phospholipid secretion as canaliculi-containing vesicles from the canalicular plasma membrane (PubMed:9366571) . In cooperation with ATP8B1, functions to protect hepatocytes from the deleterious detergent activity of bile salts (PubMed:21820390) . Does not confer multidrug resistance (PubMed:1990275) .

Clonality

Polyclonal

Conjugation

HRP

Type

Polyclonal Antibody

Applications

Enzyme-linked immunosorbent assay

Purification

Protein G Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol