RNF213 Antibody (OABF01910-100UL)
Probable E3 ubiquitin-protein ligase that may play a role in angiogenesis. May also have ATPase activity.
Product Specifications
CAS Number
9007-83-4
Gene Name
Ring finger protein 213
Gene Aliases
ALK lymphoma oligomerization partner on chromosome 17; ALO17; C17orf27; E3 ubiquitin-protein ligase RNF213; KIAA1618; MYMY2; mysterin; MYSTR; NET57; RING finger protein 213; RING-type E3 ubiquitin transferase RNF213.
Gene ID
57674
Reactivity
Human|Mouse|Rat
Immunogen
KLH conjugated synthetic peptide derived from human RNF213
Target
E3 ubiquitin-protein ligase involved in angiogenesis (PubMed:21799892, PubMed:26278786, PubMed:26766444, PubMed:26126547) . Involved in the non-canonical Wnt signaling pathway in vascular development: acts by mediating ubiquitination and degradation of FLNA and NFATC2 downstream of RSPO3, leading to inhibit the non-canonical Wnt signaling pathway and promoting vessel regression (PubMed:26766444) . Also has ATPase activity (PubMed:24658080, PubMed:26126547) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
Immunofluorescence|Immunohistochemistry-Paraffin
Purification
Protein A Purified
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions
Reconstitution & Storage Instructions
Western Blotting/Immunoblotting (WB/IB) Protocol
Western Blotting/Immunoblotting (WB/IB) Protocol
Immunohistochemistry (IHC) Protocol
Immunohistochemistry (IHC) Protocol
Immunocytochemistry (ICC) Protocol
Immunocytochemistry (ICC) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Blocking Peptide Competition Protocol (BPCP)
Blocking Peptide Competition Protocol (BPCP)
Immunoprecipitation (IP) Protocol
Immunoprecipitation (IP) Protocol
Antibody Array (AA) Protocol
Antibody Array (AA) Protocol
Concentration
1 ug/ul
Format
Liquid.// 0.01M TBS (pH 7.4) with 1% BSA, 0.03% Proclin300 and 50% glycerol
Reconstitution
-20°C
Molecular Weight
591
Fragment
IgG
NCBI Gene Symbol
RNF213
Host or Source
Rabbit
Protein Name
E3 ubiquitin-protein ligase RNF213
Gene Name URL
RNF213
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