TUSC3 Antibody (OABF01659-100UL)
Product Specifications
CAS Number
9007-83-4
Gene Name
Tumor suppressor candidate 3
Gene Aliases
D8S1992; dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit TUSC3; M33; magnesium uptake/transporter TUSC3; MagT2; mental retardation, non-syndromic, autosomal recessive, 22; MRT22; MRT7; N33; oligosaccharyl transferase subunit TUSC3; oligosaccharyltransferase 3 homolog A; OST3A; Protein N33; putative prostate cancer tumor suppressor; SLC58A2; tumor suppressor candidate 3.
Gene ID
7991
Reactivity
Bovine|Dog|Human|Mouse|Porcine|Rat
Immunogen
KLH conjugated synthetic peptide derived from human TUSC3
Target
Acts as accessory component of the N-oligosaccharyl transferase (OST) complex which catalyzes the transfer of a high mannose oligosaccharide from a lipid-linked oligosaccharide donor to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains. Involved in N-glycosylation of STT3B-dependent substrates. Specifically required for the glycosylation of a subset of acceptor sites that are near cysteine residues; in this function seems to act redundantly with MAGT1. In its oxidized form proposed to form transient mixed disulfides with a glycoprotein substrate to facilitate access of STT3B to the unmodified acceptor site. Has also oxidoreductase-independent functions in the STT3B-containing OST complex possibly involving substrate recognition.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
Enzyme-linked immunosorbent assay|Immunocytochemistry|Immunofluorescence|Immunohistochemistry-Frozen|Immunohistochemistry-Paraffin|Western blot
Purification
Protein A Purified
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions
Reconstitution & Storage Instructions
Western Blotting/Immunoblotting (WB/IB) Protocol
Western Blotting/Immunoblotting (WB/IB) Protocol
Immunohistochemistry (IHC) Protocol
Immunohistochemistry (IHC) Protocol
Immunocytochemistry (ICC) Protocol
Immunocytochemistry (ICC) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Blocking Peptide Competition Protocol (BPCP)
Blocking Peptide Competition Protocol (BPCP)
Immunoprecipitation (IP) Protocol
Immunoprecipitation (IP) Protocol
Antibody Array (AA) Protocol
Antibody Array (AA) Protocol
Concentration
1 ug/ul
Format
Liquid. Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide.
Reconstitution
-20°C
Fragment
IgG
NCBI Gene Symbol
TUSC3
Host or Source
Rabbit
Protein Name
Tumor suppressor candidate 3
Gene Name URL
TUSC3
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog