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TUSC3 Antibody (OABF01659-100UL)

Product Specifications

CAS Number

9007-83-4

Gene Name

Tumor suppressor candidate 3

Gene Aliases

D8S1992; dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit TUSC3; M33; magnesium uptake/transporter TUSC3; MagT2; mental retardation, non-syndromic, autosomal recessive, 22; MRT22; MRT7; N33; oligosaccharyl transferase subunit TUSC3; oligosaccharyltransferase 3 homolog A; OST3A; Protein N33; putative prostate cancer tumor suppressor; SLC58A2; tumor suppressor candidate 3.

Gene ID

7991

Reactivity

Bovine|Dog|Human|Mouse|Porcine|Rat

Immunogen

KLH conjugated synthetic peptide derived from human TUSC3

Target

Acts as accessory component of the N-oligosaccharyl transferase (OST) complex which catalyzes the transfer of a high mannose oligosaccharide from a lipid-linked oligosaccharide donor to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains. Involved in N-glycosylation of STT3B-dependent substrates. Specifically required for the glycosylation of a subset of acceptor sites that are near cysteine residues; in this function seems to act redundantly with MAGT1. In its oxidized form proposed to form transient mixed disulfides with a glycoprotein substrate to facilitate access of STT3B to the unmodified acceptor site. Has also oxidoreductase-independent functions in the STT3B-containing OST complex possibly involving substrate recognition.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Polyclonal Antibody

Applications

Enzyme-linked immunosorbent assay|Immunocytochemistry|Immunofluorescence|Immunohistochemistry-Frozen|Immunohistochemistry-Paraffin|Western blot

Purification

Protein A Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

1 ug/ul

Format

Liquid. Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide.

Reconstitution

-20°C

Fragment

IgG

NCBI Gene Symbol

TUSC3

Host or Source

Rabbit

Protein Name

Tumor suppressor candidate 3

Gene Name URL

TUSC3

Frequently Asked Questions

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