MFSD2A Antibody (OABF01648-100UL)
Product Specifications
CAS Number
9007-83-4
Gene Name
Major facilitator superfamily domain containing 2A
Gene Aliases
Major facilitator superfamily domain-containing protein 2A; MCPH15; MFSD2; NEDMISBA; NLS1; SLC59A1; sodium-dependent LPC symporter 1; sodium-dependent lysophosphatidylcholine symporter 1.
Gene ID
84879
Reactivity
Bovine|Chicken|Dog|Horse|Human|Mouse|Porcine|Rabbit|Rat
Immunogen
KLH conjugated synthetic peptide derived from human MFSD2A
Target
Sodium-dependent lysophosphatidylcholine (LPC) symporter, which plays an essential role for blood-brain barrier formation and function (By similarity) . Specifically expressed in endothelium of the blood-brain barrier of micro-vessels and transports LPC into the brain (By similarity) . Transport of LPC is essential because it constitutes the major mechanism by which docosahexaenoic acid (DHA), an omega-3 fatty acid that is essential for normal brain growth and cognitive function, enters the brain (PubMed:26005868) . Transports LPC carrying long-chain fatty acids such LPC oleate and LPC palmitate with a minimum acyl chain length of 14 carbons (By similarity) . Does not transport docosahexaenoic acid in unesterified fatty acid (By similarity) . Specifically required for blood-brain barrier formation and function, probably by mediating lipid transport (By similarity) . Not required for central nervous system vascular morphogenesis (By similarity) . Acts as a transporter for tunicamycin, an inhibitor of asparagine-linked glycosylation (PubMed:21677192) . In placenta, acts as a receptor for ERVFRD-1/syncytin-2 and is required for trophoblast fusion (PubMed:18988732, PubMed:23177091) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
Enzyme-linked immunosorbent assay|Flow cytometry|Immunocytochemistry|Immunofluorescence|Immunohistochemistry-Frozen|Immunohistochemistry-Paraffin|Western blot
Purification
Protein A Purified
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions
Reconstitution & Storage Instructions
Western Blotting/Immunoblotting (WB/IB) Protocol
Western Blotting/Immunoblotting (WB/IB) Protocol
Immunohistochemistry (IHC) Protocol
Immunohistochemistry (IHC) Protocol
Immunocytochemistry (ICC) Protocol
Immunocytochemistry (ICC) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Blocking Peptide Competition Protocol (BPCP)
Blocking Peptide Competition Protocol (BPCP)
Immunoprecipitation (IP) Protocol
Immunoprecipitation (IP) Protocol
Antibody Array (AA) Protocol
Antibody Array (AA) Protocol
Concentration
1 ug/ul
Format
Liquid.// Aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide.
Reconstitution
-20°C
Fragment
IgG
NCBI Gene Symbol
MFSD2A
Host or Source
Rabbit
Protein Name
Sodium-dependent lysophosphatidylcholine symporter 1
Gene Name URL
MFSD2A
Frequently Asked Questions
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