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MFSD2A Antibody (OABF01648-100UL)

Product Specifications

CAS Number

9007-83-4

Gene Name

Major facilitator superfamily domain containing 2A

Gene Aliases

Major facilitator superfamily domain-containing protein 2A; MCPH15; MFSD2; NEDMISBA; NLS1; SLC59A1; sodium-dependent LPC symporter 1; sodium-dependent lysophosphatidylcholine symporter 1.

Gene ID

84879

Reactivity

Bovine|Chicken|Dog|Horse|Human|Mouse|Porcine|Rabbit|Rat

Immunogen

KLH conjugated synthetic peptide derived from human MFSD2A

Target

Sodium-dependent lysophosphatidylcholine (LPC) symporter, which plays an essential role for blood-brain barrier formation and function (By similarity) . Specifically expressed in endothelium of the blood-brain barrier of micro-vessels and transports LPC into the brain (By similarity) . Transport of LPC is essential because it constitutes the major mechanism by which docosahexaenoic acid (DHA), an omega-3 fatty acid that is essential for normal brain growth and cognitive function, enters the brain (PubMed:26005868) . Transports LPC carrying long-chain fatty acids such LPC oleate and LPC palmitate with a minimum acyl chain length of 14 carbons (By similarity) . Does not transport docosahexaenoic acid in unesterified fatty acid (By similarity) . Specifically required for blood-brain barrier formation and function, probably by mediating lipid transport (By similarity) . Not required for central nervous system vascular morphogenesis (By similarity) . Acts as a transporter for tunicamycin, an inhibitor of asparagine-linked glycosylation (PubMed:21677192) . In placenta, acts as a receptor for ERVFRD-1/syncytin-2 and is required for trophoblast fusion (PubMed:18988732, PubMed:23177091) .

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Polyclonal Antibody

Applications

Enzyme-linked immunosorbent assay|Flow cytometry|Immunocytochemistry|Immunofluorescence|Immunohistochemistry-Frozen|Immunohistochemistry-Paraffin|Western blot

Purification

Protein A Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

1 ug/ul

Format

Liquid.// Aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide.

Reconstitution

-20°C

Fragment

IgG

NCBI Gene Symbol

MFSD2A

Host or Source

Rabbit

Protein Name

Sodium-dependent lysophosphatidylcholine symporter 1

Gene Name URL

MFSD2A

Frequently Asked Questions

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