What is the catalog number for ULK1 Antibody (Phospho-Ser556) (OABF01248-100UL)?

The catalog number for ULK1 Antibody (Phospho-Ser556) (OABF01248-100UL) is OABF01248-100UL.

What sizes are available for ULK1 Antibody (Phospho-Ser556) (OABF01248-100UL)?

ULK1 Antibody (Phospho-Ser556) (OABF01248-100UL) is available in the following size(s): 100 µL.

Is ULK1 Antibody (Phospho-Ser556) (OABF01248-100UL) in stock?

ULK1 Antibody (Phospho-Ser556) (OABF01248-100UL) is currently made to order / not held in immediate stock. Contact us for lead time.

How many freeze-thaw cycles can this product tolerate?

We recommend aliquoting the product upon receipt to avoid repeated freeze-thaw cycles, which can reduce activity and stability. This is your responsibility once the product has been delivered.

Is antigen retrieval required for IHC with this antibody?

Recommended antigen retrieval methods, where applicable, are listed on the datasheet under the IHC protocol section.

What temperature does this product ship at?

Shipping temperature is chosen based on the product’s stability needs, ranging from ambient to dry ice, and is indicated on the product page. Any related shipping fee is shown clearly in your quotation.

ULK1 Antibody (Phospho-Ser556) (OABF01248-100UL)

Product Specifications

CAS Number

9007-83-4

Gene Name

Unc-51 like autophagy activating kinase 1

Gene Aliases

ATG1; ATG1 autophagy related 1 homolog; ATG1A; autophagy-related protein 1 homolog; hATG1; serine/threonine-protein kinase ULK1; UNC51; Unc51.1; Unc-51-like kinase 1.

Gene ID

8408

Reactivity

Horse|Human|Mouse|Porcine|Rat

Immunogen

KLH conjugated synthetic phosphopeptide derived from human ATG1 around the phosphorylation site of Ser556

Target

Serine/threonine-protein kinase involved in autophagy in response to starvation. Acts upstream of phosphatidylinositol 3-kinase PIK3C3 to regulate the formation of autophagophores, the precursors of autophagosomes. Part of regulatory feedback loops in autophagy: acts both as a downstream effector and negative regulator of mammalian target of rapamycin complex 1 (mTORC1) via interaction with RPTOR. Activated via phosphorylation by AMPK and also acts as a regulator of AMPK by mediating phosphorylation of AMPK subunits PRKAA1, PRKAB2 and PRKAG1, leading to negatively regulate AMPK activity. May phosphorylate ATG13/KIAA0652 and RPTOR; however such data need additional evidences. Plays a role early in neuronal differentiation and is required for granule cell axon formation. May also phosphorylate SESN2 and SQSTM1 to regulate autophagy (PubMed:25040165) .

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Polyclonal Antibody

Applications

Purification

Protein A Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol