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Podocin Polyclonal Antibody

Product Specifications

CAS Number

9007-83-4

Gene Name

Forkhead box O3

Gene Aliases

AF6q21; AF6q21 protein; FKHRL1; FKHRL1P2; forkhead box O3A; forkhead box protein O3; forkhead homolog (rhabdomyosarcoma) like 1; forkhead in rhabdomyosarcoma-like 1; forkhead, Drosophila, homolog of, in rhabdomyosarcoma-like 1; FOXO2; FOXO3A; FOXO3A-.

Gene ID

2309

Swiss Prot

P32926

Reactivity

Human

Immunogen

A synthesized peptide derived from human Phospho-FOXO3 (S253)

Clonality

Recombinant Monoclonal

Conjugation

Unconjugated

Type

Polyclonal Antibody

Purification

Affinity Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Dilution

Transcriptional activator which triggers apoptosis in the absence of survival factors, including neuronal cell death upon oxidative stress (PubMed:10102273, PubMed:16751106) . Recognizes and binds to the DNA sequence 5'-[AG]TAAA[TC]A-3' (PubMed:21329882) . Participates in post-transcriptional regulation of MYC: following phosphorylation by MAPKAPK5, promotes induction of miR-34b and miR-34c expression, 2 post-transcriptional regulators of MYC that bind to the 3'UTR of MYC transcript and prevent its translation (PubMed:21329882) . In response to metabolic stress, translocates into the mitochondria where it promotes mtDNA transcription (PubMed:23283301) .

Format

Liquid

Reconstitution

-20°C or -80°C

NCBI Gene Symbol

FOXO3

Protein Name

Forkhead box protein O3

Gene Name URL

FOXO3

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