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Human H2AX Antibody (Phospho-Ser139)

Product Specifications

CAS Number

9007-83-4

Gene Name

H2A.X variant histone

Gene Aliases

H2A.X, H2A/X, H2AFX

Gene ID

3014

Swiss Prot

P16104

Accession Number

NP_002096.1

Reactivity

Mouse, Rat

Immunogen

A synthetic phospho-peptide corresponding to residues surrounding Ser139 of human phospho histone H2A.X.

Target

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene encodes a replication-independent histone that is a member of the histone H2A family, and generates two transcripts through the use of the conserved stem-loop termination motif, and the polyA addition motif.

Clonality

Monoclonal

Clone

HisH2AXS139-1B3

Conjugation

Unconjugated

Type

Monoclonal Antibody

Applications

FC, WB

Purification

Protein A+G

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Format

Liquid. 1X PBS, 0.02% NaN3, 50% Glycerol, 0.1% BSA.

Reconstitution

-20C

Fragment

Rabbit IgG1k

NCBI Gene Symbol

H2AX

Host or Source

Rabbit

Protein Name

Histone H2AX

Gene Name URL

H2AX

Nucleotide Accession Number

NM_002105.2

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