Human H2AX Antibody (Phospho-Ser139)
Product Specifications
CAS Number
9007-83-4
Gene Name
H2A.X variant histone
Gene Aliases
H2A.X, H2A/X, H2AFX
Gene ID
3014
Swiss Prot
P16104
Accession Number
NP_002096.1
Reactivity
Mouse, Rat
Immunogen
A synthetic phospho-peptide corresponding to residues surrounding Ser139 of human phospho histone H2A.X.
Target
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene encodes a replication-independent histone that is a member of the histone H2A family, and generates two transcripts through the use of the conserved stem-loop termination motif, and the polyA addition motif.
Clonality
Monoclonal
Clone
HisH2AXS139-1B3
Conjugation
Unconjugated
Type
Monoclonal Antibody
Applications
FC, WB
Purification
Protein A+G
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions
Reconstitution & Storage Instructions
Western Blotting/Immunoblotting (WB/IB) Protocol
Western Blotting/Immunoblotting (WB/IB) Protocol
Immunohistochemistry (IHC) Protocol
Immunohistochemistry (IHC) Protocol
Immunocytochemistry (ICC) Protocol
Immunocytochemistry (ICC) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Blocking Peptide Competition Protocol (BPCP)
Blocking Peptide Competition Protocol (BPCP)
Immunoprecipitation (IP) Protocol
Immunoprecipitation (IP) Protocol
Antibody Array (AA) Protocol
Antibody Array (AA) Protocol
Format
Liquid. 1X PBS, 0.02% NaN3, 50% Glycerol, 0.1% BSA.
Reconstitution
-20C
Fragment
Rabbit IgG1k
NCBI Gene Symbol
H2AX
Host or Source
Rabbit
Protein Name
Histone H2AX
Gene Name URL
H2AX
Nucleotide Accession Number
NM_002105.2
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