Human EIF4EBP1 Antibody (Phospho-Thr37/46)
Product Specifications
CAS Number
9007-83-4
Gene Name
Eukaryotic translation initiation factor 4E binding protein 1
Gene Aliases
BP-1, 4EBP1, 4E-BP1, PHAS-I
Gene ID
1978
Swiss Prot
Q13541
Accession Number
NP_004086.1
Reactivity
Mouse, Rat
Immunogen
A synthetic phospho-peptide corresponding to residues surrounding Thr37/46 of human phospho 4E-BP1.
Target
This gene encodes one member of a family of translation repressor proteins. The protein directly interacts with eukaryotic translation initiation factor 4E (eIF4E), which is a limiting component of the multisubunit complex that recruits 40S ribosomal subunits to the 5' end of mRNAs. Interaction of this protein with eIF4E inhibits complex assembly and represses translation. This protein is phosphorylated in response to various signals including UV irradiation and insulin signaling, resulting in its dissociation from eIF4E and activation of mRNA translation.
Clonality
Monoclonal
Clone
4EB1T37T46-A5
Conjugation
Unconjugated
Type
Monoclonal Antibody
Applications
FC, WB, IHC
Purification
Protein A+G
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions
Reconstitution & Storage Instructions
Western Blotting/Immunoblotting (WB/IB) Protocol
Western Blotting/Immunoblotting (WB/IB) Protocol
Immunohistochemistry (IHC) Protocol
Immunohistochemistry (IHC) Protocol
Immunocytochemistry (ICC) Protocol
Immunocytochemistry (ICC) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Blocking Peptide Competition Protocol (BPCP)
Blocking Peptide Competition Protocol (BPCP)
Immunoprecipitation (IP) Protocol
Immunoprecipitation (IP) Protocol
Antibody Array (AA) Protocol
Antibody Array (AA) Protocol
Format
Liquid. 1X PBS, 0.02% NaN3, 50% Glycerol, 0.1% BSA.
Reconstitution
-20C
Fragment
Rabbit IgG1k
NCBI Gene Symbol
EIF4EBP1
Host or Source
Rabbit
Protein Name
Eukaryotic translation initiation factor 4E-binding protein 1
Gene Name URL
EIF4EBP1
Nucleotide Accession Number
NM_004095.3
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
BNC400026-100 1x 100 µL
ACTH (Adrenocorticotrophic Hormone) (AH26), CF640R conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC472783-500 1x 500 µL
C1QA / Complement C1q A-Chain (C1QA/2783), CF647 conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC680999-100 1x 100 µL
Cytokeratin, pan (Cocktail PAN-CK), CF568 conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC682284-100 1x 100 µL
Human IgG4 (Ig Heavy Constant Gamma 4) (G4m Marker) (rIGHG4/1345), CF568 conjugate, 0.1mg/mL
Sign In for Pricing
View Details