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Human BTK Antibody (Phospho-Tyr223)

Product Specifications

CAS Number

9007-83-4

Gene Name

Bruton tyrosine kinase

Gene Aliases

AT, ATK, BPK, XLA, IMD1, AGMX1, IGHD3, PSCTK1

Gene ID

695

Swiss Prot

Q06187

Accession Number

NP_000052.1

Reactivity

Mouse, Rat

Immunogen

A synthetic phospho-peptide corresponding to residues surrounding Tyr223 of human phospho Btk

Target

The protein encoded by this gene plays a crucial role in B-cell development. Mutations in this gene cause X-linked agammaglobulinemia type 1, which is an immunodeficiency characterized by the failure to produce mature B lymphocytes, and associated with a failure of Ig heavy chain rearrangement. Alternative splicing results in multiple transcript variants encoding different isoforms.

Clonality

Monoclonal

Clone

BtkY223-B4

Conjugation

Unconjugated

Type

Monoclonal Antibody

Applications

FC

Purification

Protein A+G

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Format

Liquid. 1X PBS, 0.02% NaN3, 50% Glycerol, 0.1% BSA.

Reconstitution

-20C

Fragment

Rabbit IgG1k

NCBI Gene Symbol

BTK

Host or Source

Rabbit

Protein Name

Tyrosine-protein kinase BTK

Gene Name URL

BTK

Nucleotide Accession Number

NM_000061.2

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