Human PLCG2 Antibody : APC (Phospho-Tyr759)
Product Specifications
CAS Number
9007-83-4
Gene Name
Phospholipase C gamma 2
Gene Aliases
FCAS3, APLAID, PLC-IV, PLC-gamma-2
Gene ID
5336
Swiss Prot
P16885
Accession Number
NP_002652.2
Reactivity
Mouse, Rat
Immunogen
A synthetic phospho-peptide corresponding to residues surrounding Tyr759 of human phospho PLCγ2.
Target
The protein encoded by this gene is a transmembrane signaling enzyme that catalyzes the conversion of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate to 1D-myo-inositol 1,4,5-trisphosphate (IP3) and diacylglycerol (DAG) using calcium as a cofactor. IP3 and DAG are second messenger molecules important for transmitting signals from growth factor receptors and immune system receptors across the cell membrane. Mutations in this gene have been found in autoinflammation, antibody deficiency, and immune dysregulation syndrome and familial cold autoinflammatory syndrome 3.
Clonality
Monoclonal
Clone
PLCG2Y759-G3
Conjugation
APC: Allophycocyanin
Type
Monoclonal Antibody
Applications
FC
Purification
Protein A+G
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions
Reconstitution & Storage Instructions
Western Blotting/Immunoblotting (WB/IB) Protocol
Western Blotting/Immunoblotting (WB/IB) Protocol
Immunohistochemistry (IHC) Protocol
Immunohistochemistry (IHC) Protocol
Immunocytochemistry (ICC) Protocol
Immunocytochemistry (ICC) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Blocking Peptide Competition Protocol (BPCP)
Blocking Peptide Competition Protocol (BPCP)
Immunoprecipitation (IP) Protocol
Immunoprecipitation (IP) Protocol
Antibody Array (AA) Protocol
Antibody Array (AA) Protocol
Format
Liquid. 1X PBS, 0.09% NaN3, 0.2% BSA.
Reconstitution
2-8C
Fragment
Rabbit IgG1k
NCBI Gene Symbol
PLCG2
Host or Source
Rabbit
Protein Name
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2
Gene Name URL
PLCG2
Nucleotide Accession Number
NM_002661.4
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