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UACA Antibody

Product Specifications

CAS Number

9007-83-4

Gene Name

Uveal autoantigen with coiled-coil domains and ankyrin repeats

Gene Aliases

Nuclear membrane binding protein; NUCLING; uveal autoantigen with coiled-coil domains and ankyrin repeats.

Gene ID

55075

Swiss Prot

Q9BZF9

Accession Number

NP_001008225.1

Reactivity

Human, Mouse, Rat

Immunogen

UACA

Target

Regulates APAF1 expression and plays an important role in the regulation of stress-induced apoptosis. Promotes apoptosis by regulating three pathways, apoptosome up-regulation, LGALS3/galectin-3 down-regulation and NF-kappa-B inactivation. Regulates the redistribution of APAF1 into the nucleus after proapoptotic stress. Down-regulates the expression of LGALS3 by inhibiting NFKB1 (By similarity) .

Clonality

Polyclonal

Type

Polyclonal Antibody

Applications

Western blot

Purification

Affinity purification

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Format

Liquid

Reconstitution

Store at +4C. For long term storage, aliquote and store at -20C. Avoid freeze/thaw cycles.

Molecular Weight

163kDa

Fragment

IgG

NCBI Gene Symbol

UACA

Host or Source

Rabbit

Protein Name

Uveal autoantigen with coiled-coil domains and ankyrin repeats

Gene Name URL

UACA

Nucleotide Accession Number

NM_001008224.1

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