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CKAP5 Antibody

Product Specifications

Gene Name

Cytoskeleton associated protein 5

Gene Aliases

TOG, MSPS, TOGp, CHTOG, ch-TOG

Gene ID

9793

Swiss Prot

Q14008

Accession Number

NP_001008938.1

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant Protein

Target

Binds to the plus end of microtubules and regulates microtubule dynamics and microtubule organization. Acts as processive microtubule polymerase. Promotes cytoplasmic microtubule nucleation and elongation. Plays a major role in organizing spindle poles. In spindle formation protects kinetochore microtubules from depolymerization by KIF2C and has an essential role in centrosomal microtubule assembly independently of KIF2C activity. Contributes to centrosome integrity. Acts as component of the TACC3/ch-TOG/clathrin complex proposed to contribute to stabilization of kinetochore fibers of the mitotic spindle by acting as inter-microtubule bridge. The TACC3/ch-TOG/clathrin complex is required for the maintenance of kinetochore fiber tension.

Clonality

Polyclonal

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity purification

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Format

Liquid

Reconstitution

Store at +4C. For long term storage, aliquote and store at -20C. Avoid freeze/thaw cycles.

Molecular Weight

225 kDa

Fragment

IgG

NCBI Gene Symbol

CKAP5

Host or Source

Rabbit

Protein Name

Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha

Gene Name URL

CKAP5

CAS Number

9007-83-4

Nucleotide Accession Number

NM_001008938.3

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