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PDK3 Antibody

Product Specifications

CAS Number

9007-83-4

Gene Name

Pyruvate dehydrogenase kinase 3

Gene Aliases

CMTX6, GS1-358P8.4

Gene ID

5165

Swiss Prot

Q15120

Accession Number

NP_001135858.1

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant Protein

Target

Inhibits pyruvate dehydrogenase activity by phosphorylation of the E1 subunit PDHA1, and thereby regulates glucose metabolism and aerobic respiration. Can also phosphorylate PDHA2. Decreases glucose utilization and increases fat metabolism in response to prolonged fasting, and as adaptation to a high-fat diet. Plays a role in glucose homeostasis and in maintaining normal blood glucose levels in function of nutrient levels and under starvation. Plays a role in the generation of reactive oxygen species.

Clonality

Polyclonal

Type

Polyclonal Antibody

Applications

WB, IHC

Purification

Affinity purification

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Format

Liquid

Reconstitution

Store at +4C. For long term storage, aliquote and store at -20C. Avoid freeze/thaw cycles.

Molecular Weight

47 kDa

Fragment

IgG

NCBI Gene Symbol

PDK3

Host or Source

Rabbit

Protein Name

Neurocalcin-delta

Gene Name URL

PDK3

Nucleotide Accession Number

NM_001142386.2

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