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RASSF5 Antibody

Product Specifications

CAS Number

9007-83-4

Gene Name

Ras association domain family member 5

Gene Aliases

Maxp1; new ras effector 1; NORE1; NORE1A; NORE1B; novel Ras effector 1; Rap1-binding protein; RAPL; Ras association (RalGDS/AF-6) domain family 5; Ras association (RalGDS/AF-6) domain family member 5; ras association domain-containing protein 5; Ras effector-like protein; RASSF3; regulator for cell adhesion and polarization enriched in lymphoid tissue; Regulator for cell adhesion and polarization enriched in lymphoid tissues; tumor suppressor RASSF3.

Gene ID

83593

Swiss Prot

Q8WWW0

Accession Number

NP_872604.1

Reactivity

Human, Mouse, Rat

Immunogen

RASSF5

Target

Potential tumor suppressor. Seems to be involved in lymphocyte adhesion by linking RAP1A activation upon T-cell receptor or chemokine stimulation to integrin activation. Isoform 2 stimulates lymphocyte polarization and the patch-like distribution of ITGAL/LFA-1, resulting in an enhanced adhesion to ICAM1. Together with RAP1A may participate in regulation of microtubule growth. The association of isoform 2 with activated RAP1A is required for directional movement of endothelial cells during wound healing. May be involved in regulation of Ras apoptotic function. The RASSF5-STK4/MST1 complex may mediate HRAS and KRAS induced apoptosis.

Clonality

Polyclonal

Type

Polyclonal Antibody

Applications

Western blot

Purification

Affinity purification

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Format

Liquid

Reconstitution

Store at +4C. For long term storage, aliquote and store at -20C. Avoid freeze/thaw cycles.

Molecular Weight

47kDa

Fragment

IgG

NCBI Gene Symbol

RASSF5

Host or Source

Rabbit

Protein Name

Ras association domain-containing protein 5

Gene Name URL

RASSF5

Nucleotide Accession Number

NM_182663.3

Frequently Asked Questions

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