BCL6-IN-4
BCL6-IN-4 is a potent B-cell lymphoma 6 (BCL6) inhibitor with an IC50 of 97 nM. BCL6-IN-4 has anti-tumor activities[1].
Product Specifications
CAS Number
[2253879-65-9]
UNSPSC
12352005
Target
Bcl-2 Family
Type
Reference compound
Related Pathways
Apoptosis
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/bcl6-in-4.html
Concentration
10mM
Purity
99.72
Solubility
DMSO : 73.33 mg/mL (ultrasonic)
Smiles
O=C1N(CCC(C)(O)C)C2=CC(NC3=NC(N4CC(C)(C)OC(C)(C)C4)=NC=C3Cl)=CC=C2N1C
Molecular Formula
C25H35ClN6O3
Molecular Weight
503.04
References & Citations
[1]Benjamin R Bellenie, et al. Achieving In Vivo Target Depletion through the Discovery and Optimization of Benzimidazolone BCL6 Degraders. J Med Chem. 2020 Apr 23;63 (8) :4047-4068.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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