SPDYA Antibody

Product Specifications

CAS Number

9007-83-4

Gene Name

Speedy/RINGO cell cycle regulator family member A

Gene Aliases

Epididymis secretory sperm binding protein; hSpy/Ringo A; rapid inducer of G2/M progression in oocytes A; RINGO A; RINGO3; RINGOA; SPDY1; speedy homolog A; speedy protein A; speedy-1; SPY1.

Gene ID

245711

Swiss Prot

Q5MJ70

Accession Number

NP_001008779.1

Reactivity

Human, Mouse, Rat

Immunogen

SPDYA

Target

Regulates the G1/S phase transition of the cell cycle by binding and activating CDK1 and CDK2 (PubMed:12972555) . Contributes to CDK2 activation without promoting CDK2 phosphorylation, by inducing a conformation change of the CDK2 T-loop that obstructs the substrate-binding cleft prior to kinase activation (PubMed:28666995) . Mediates cell survival during the DNA damage process through activation of CDK2 (PubMed:12839962) .

Clonality

Polyclonal

Type

Polyclonal Antibody

Applications

Western blot

Purification

Affinity purification

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol