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TYK2 Antibody (Phospho-Tyr1054)

Product Specifications

CAS Number

9007-83-4

Gene Name

Tyrosine kinase 2

Gene Aliases

JTK1, IMD35

Gene ID

7297

Swiss Prot

P29597

Accession Number

NP_003322.3

Reactivity

Human, Mouse

Immunogen

A phospho-Serpecific peptide corresponding-Thro residues-Serurrounding-Tyr1054 of human-ThrYK2

Target

This gene encodes a member of the tyrosine kinase and, more specifically, the Janus kinases (JAKs) protein families. This protein associates with the cytoplasmic domain of type I and type II cytokine receptors and promulgate cytokine signals by phosphorylating receptor subunits. It is also component of both the type I and type III interferon signaling pathways. As such, it may play a role in anti-viral immunity. A mutation in this gene has been associated with hyperimmunoglobulin E syndrome (HIES) - a primary immunodeficiency characterized by elevated serum immunoglobulin E.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity purified against immunogen

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Format

Liquid

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Reconstitution

Store at -20C. Avoid repeated freeze/thaw cycles.

Molecular Weight

140 kDa

Fragment

IgG

NCBI Gene Symbol

TYK2

Host or Source

Rabbit

Protein Name

Non-receptor tyrosine-protein kinase TYK2

Gene Name URL

TYK2

Nucleotide Accession Number

NM_003331.4

Frequently Asked Questions

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