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INSR Antibody (Phospho-Tyr1150/IGF1R-Tyr1135)

Selected Variant

OAAN02738-100UL

Size: 100 µL

Product Specifications

CAS Number

9007-83-4

Gene Name

Insulin receptor

Gene Aliases

HHF5, CD220

Gene ID

3643

Swiss Prot

P06213

Accession Number

NP_000199.2

Reactivity

Human, Mouse, Rat

Immunogen

A phospho-Serpecific peptide corresponding-Thro residues-Serurrounding-Tyr1150 of human INSR and-Tyr1135 of human IGF1R_x005F

Target

This receptor binds insulin-like growth factor with a high affinity. It has tyrosine kinase activity. The insulin-like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

Varies by lot. See vial for exact concentration.

Format

Liquid//PBS with 0.02% sodium azide, 50% glycerol (pH 7.3)

Reconstitution

Store at -20° C. Avoid repeated freeze/thaw cycles.

Molecular Weight

155 kDa

Fragment

IgG

NCBI Gene Symbol

INSR

Host or Source

Rabbit

Protein Name

Insulin receptor

Gene Name URL

INSR

Nucleotide Accession Number

NM_000208.3

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