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(R)-MLN-4760

Product Specifications

UNSPSC Description

(R)-MLN-4760, the R-enantiomer of MLN-4760, is an ACE2 inhibitor, with an IC50 of 8.4 μM. (R)-MLN-4760 is the less active isomer[1].

Target Antigen

Angiotensin-converting Enzyme (ACE)

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Neuroscience-Neuromodulation

Field of Research

Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/r-mln-4760.html

Purity

99.51

Solubility

DMSO : 14.29 mg/mL (ultrasonic)

Smiles

O=C(O)[C@H](CC1=CN=CN1CC2=CC(Cl)=CC(Cl)=C2)N[C@@H](C(O)=O)CC(C)C

Molecular Weight

428.31

References & Citations

[1]Dales NA, et, al. Substrate-based design of the first class of angiotensin-converting enzyme-related carboxypeptidase (ACE2) inhibitors. J Am Chem Soc. 2002 Oct 9;124(40):11852-3.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-19414A/R-MLN-4760-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-19414A/R-MLN-4760-SDS-MedChemExpress.pdf

Clinical Information

No Development Reported

CAS Number

305335-29-9

Available Sizes

Curated Selection

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