PDE6B Antibody
Product Specifications
CAS Number
9007-83-4
Gene Name
Phosphodiesterase 6B
Gene Aliases
Rd1, PDEB, RP40, CSNB3, CSNBAD2, GMP-PDEbeta
Gene ID
5158
Swiss Prot
P35913
Accession Number
NP_000274.2
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant protein of human PDE6B
Target
Photon absorption triggers a signaling cascade in rod photoreceptors that activates cGMP phosphodiesterase (PDE), resulting in the rapid hydrolysis of cGMP, closure of cGMP-gated cation channels, and hyperpolarization of the cell. PDE is a peripheral membrane heterotrimeric enzyme made up of alpha, beta, and gamma subunits. This gene encodes the beta subunit. Mutations in this gene result in retinitis pigmentosa and autosomal dominant congenital stationary night blindness. Multiple transcript variants encoding different isoforms have been found for this gene.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
WB, IHC
Purification
Affinity purified against immunogen
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions
Reconstitution & Storage Instructions
Western Blotting/Immunoblotting (WB/IB) Protocol
Western Blotting/Immunoblotting (WB/IB) Protocol
Immunohistochemistry (IHC) Protocol
Immunohistochemistry (IHC) Protocol
Immunocytochemistry (ICC) Protocol
Immunocytochemistry (ICC) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Blocking Peptide Competition Protocol (BPCP)
Blocking Peptide Competition Protocol (BPCP)
Immunoprecipitation (IP) Protocol
Immunoprecipitation (IP) Protocol
Antibody Array (AA) Protocol
Antibody Array (AA) Protocol
Format
Liquid
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Reconstitution
Store at -20C. Avoid repeated freeze/thaw cycles.
Molecular Weight
98 kDa
Fragment
IgG
NCBI Gene Symbol
PDE6B
Host or Source
Rabbit
Protein Name
Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit beta
Gene Name URL
PDE6B
Nucleotide Accession Number
NM_000283.3
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
ARP39760_P050-HRP 100 µL
SOX6 Antibody - middle region : HRP (ARP39760_P050-HRP)
Sign In for Pricing
View Details 
21514124 3x 1.0µg DNA
GIMAP8 CRISPRa sgRNA lentivector (set of three targets)(Mouse)
Sign In for Pricing
View Details 