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FUS Antibody

Product Specifications

CAS Number

9007-83-4

Gene Name

FUS RNA binding protein

Gene Aliases

TLS, ALS6, ETM4, FUS1, POMP75, altFUS, HNRNPP2

Gene ID

2521

Swiss Prot

P35637

Accession Number

NP_001164105.1

Reactivity

Human, Mouse, Rat

Target

This gene encodes a multifunctional protein component of the heterogeneous nuclear ribonucleoprotein (hnRNP) complex. The hnRNP complex is involved in pre-mRNA splicing and the export of fully processed mRNA to the cytoplasm. This protein belongs to the FET family of RNA-binding proteins which have been implicated in cellular processes that include regulation of gene expression, maintenance of genomic integrity and mRNA/microRNA processing. Alternative splicing results in multiple transcript variants. Defects in this gene result in amyotrophic lateral sclerosis type 6.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Polyclonal Antibody

Sequence

TIESVADYFKQIGIIKTNKKTGQPMINLYTDRETGKLKGEATVSFDDPPSAKAAIDWFDGKEFSGNPIKVSFATRRADFNRGGGNGRGGRGRGGPMGRGGYGGGGSGGGGRGGFPSGGGGGGGQQRAGDWKCPNPTCENMNFSWRNECNQCKAPKPDGPGGGPGGSHMGGNYGDDRRGGRGGYDRGGYRGRGGDRGGFRGGRGGGDRGGFGPGKMDSRGEHRQDRRERPY

Applications

WB, IHC, IF

Purification

Affinity purification

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Format

Liquid// PBS with 0.02% sodium azide with 50% glycerol (pH 7.3)

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Reconstitution

Store at -20° C. Avoid repeated freeze/thaw cycles.

Molecular Weight

53 kDa

Fragment

IgG

NCBI Gene Symbol

FUS

Host or Source

Rabbit

Protein Name

RNA-binding protein FUS

Gene Name URL

FUS

Nucleotide Accession Number

NM_001170634.1

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