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COMP Antibody

Product Specifications

CAS Number

9007-83-4

Gene Name

Cartilage oligomeric matrix protein

Gene Aliases

MED, CTS2, EDM1, EPD1, TSP5, PSACH, THBS5

Gene ID

1311

Swiss Prot

P49747

Accession Number

NP_000086.2

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant protein of human COMP

Target

The protein encoded by this gene is a noncollagenous extracellular matrix (ECM) protein. It consists of five identical glycoprotein subunits, each with EGF-like and calcium-binding (thrombospondin-like) domains. Oligomerization results from formation of a five-stranded coiled coil and disulfides. Binding to other ECM proteins such as collagen appears to depend on divalent cations. Mutations can cause the osteochondrodysplasias pseudochondroplasia (PSACH) and multiple epiphyseal dysplasia (MED) .

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Polyclonal Antibody

Applications

WB, IHC, IF

Purification

Affinity purified against immunogen

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Format

Liquid.// PBS, pH 7.3, with 0.02% sodium azide and 50% glycerol.

Reconstitution

Store at -20C. Avoid repeated freeze/thaw cycles.

Molecular Weight

82 kDa

Fragment

IgG

NCBI Gene Symbol

COMP

Host or Source

Rabbit

Protein Name

Cartilage oligomeric matrix protein

Gene Name URL

COMP

Nucleotide Accession Number

NM_000095.2

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