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QDPR Antibody

Product Specifications

CAS Number

9007-83-4

Gene Name

Quinoid dihydropteridine reductase

Gene Aliases

DHPR, PKU2, HDHPR, SDR33C1

Gene ID

5860

Swiss Prot

P09417

Accession Number

NP_000311.2

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant protein of human QDPR

Target

This gene encodes the enzyme dihydropteridine reductase, which catalyzes the NADH-mediated reduction of quinonoid dihydrobiopterin. This enzyme is an essential component of the pterin-dependent aromatic amino acid hydroxylating systems. Mutations in this gene resulting in QDPR deficiency include aberrant splicing, amino acid substitutions, insertions, or premature terminations. Dihydropteridine reductase deficiency presents as atypical phenylketonuria due to insufficient production of biopterin, a cofactor for phenylalanine hydroxylase.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Polyclonal Antibody

Applications

WB, IHC

Purification

Affinity purified against immunogen

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Format

Liquid

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Reconstitution

Store at -20C. Avoid repeated freeze/thaw cycles.

Molecular Weight

25 kDa

Fragment

IgG

NCBI Gene Symbol

QDPR

Host or Source

Rabbit

Protein Name

Dihydropteridine reductase

Gene Name URL

QDPR

Nucleotide Accession Number

NM_000320.2

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