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UHRF2 Antibody

Product Specifications

CAS Number

9007-83-4

Gene Name

Ubiquitin like with PHD and ring finger domains 2

Gene Aliases

NIRF, URF2, RNF107, TDRD23

Gene ID

115426

Swiss Prot

Q96PU4

Accession Number

NP_690856.1

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant protein of human UHRF2

Target

This gene encodes a nuclear protein which is involved in cell-cycle regulation. The encoded protein is a ubiquitin-ligase capable of ubiquinating PCNP (PEST-containing nuclear protein), and together they may play a role in tumorigenesis. The encoded protein contains an NIRF_N domain, a PHD finger, a set- and ring-associated (SRA) domain, and a RING finger domain and several of these domains have been shown to be essential for the regulation of cell proliferation. This protein may also have a role in intranuclear degradation of polyglutamine aggregates. Alternative splicing results in multiple transcript variants some of which are non-protein coding.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Polyclonal Antibody

Applications

WB, IHC, IF

Purification

Affinity purified against immunogen

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Format

Liquid.// PBS, pH 7.3, with 0.02% sodium azide and 50% glycerol.

Reconstitution

Store at -20C. Avoid repeated freeze/thaw cycles.

Molecular Weight

90 kDa

Fragment

IgG

NCBI Gene Symbol

UHRF2

Host or Source

Rabbit

Protein Name

E3 ubiquitin-protein ligase UHRF2

Gene Name URL

UHRF2

Nucleotide Accession Number

NM_152896.2

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