SFTPC Antibody
Product Specifications
Gene Name
Surfactant protein C
Gene Aliases
SP5, SP-C, PSP-C, SFTP2, SMDP2, BRICD6
Gene ID
6440
Swiss Prot
P11686
Accession Number
NP_001165828.1
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1-197 of human SFTPC.
Target
This gene encodes the pulmonary-associated surfactant protein C (SPC), an extremely hydrophobic surfactant protein essential for lung function and homeostasis after birth. Pulmonary surfactant is a surface-active lipoprotein complex composed of 90% lipids and 10% proteins which include plasma proteins and apolipoproteins SPA, SPB, SPC and SPD. The surfactant is secreted by the alveolar cells of the lung and maintains the stability of pulmonary tissue by reducing the surface tension of fluids that coat the lung. Multiple mutations in this gene have been identified, which cause pulmonary surfactant metabolism dysfunction type 2, also called pulmonary alveolar proteinosis due to surfactant protein C deficiency, and are associated with interstitial lung disease in older infants, children, and adults. Alternatively spliced transcript variants encoding different protein isoforms have been identified.
Clonality
Polyclonal
Type
Polyclonal Antibody
Applications
WB, IHC
Purification
Affinity purified
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions
Reconstitution & Storage Instructions
Western Blotting/Immunoblotting (WB/IB) Protocol
Western Blotting/Immunoblotting (WB/IB) Protocol
Immunohistochemistry (IHC) Protocol
Immunohistochemistry (IHC) Protocol
Immunocytochemistry (ICC) Protocol
Immunocytochemistry (ICC) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Blocking Peptide Competition Protocol (BPCP)
Blocking Peptide Competition Protocol (BPCP)
Immunoprecipitation (IP) Protocol
Immunoprecipitation (IP) Protocol
Antibody Array (AA) Protocol
Antibody Array (AA) Protocol
Format
Liquid.// PBS with 0.02% sodium azide, 50% glycerol, pH 7.3
Reconstitution
Store at -20C. Avoid repeated freeze/thaw cycles.
Molecular Weight
21 kDa
Fragment
IgG
NCBI Gene Symbol
SFTPC
Host or Source
Rabbit
Protein Name
Pulmonary surfactant-associated protein C
Gene Name URL
SFTPC
CAS Number
9007-83-4
Nucleotide Accession Number
NM_001172357.1
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
GTR15080515 1 Vial
Lentiviral human PRKAA2 shRNA (UAS) - Lentiviral human PRKAA2 shRNA (UAS) plasmid
Ask
View Details 
