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AKR7A2 Antibody

Product Specifications

CAS Number

9007-83-4

Gene Name

Aldo-keto reductase family 7 member A2

Gene Aliases

AFAR; AFAR1; AFB1 aldehyde reductase 1; AFB1-AR 1; AFB1-AR1; aflatoxin aldehyde reductase; aflatoxin B1 aldehyde reductase member 2; aflatoxin beta1 aldehyde reductase; AKR7; aldoketoreductase 7; epididymis secretory sperm binding protein Li 166mP; HEL-S-166mP; SSA reductase; succinic semialdehyde reductase.

Gene ID

8574

Swiss Prot

O43488

Accession Number

NP_003680.2

Reactivity

Human, Mouse

Immunogen

AKR7A2

Target

Catalyzes the NADPH-dependent reduction of succinic semialdehyde to gamma-hydroxybutyrate. May have an important role in producing the neuromodulator gamma-hydroxybutyrate (GHB) . Has broad substrate specificity. Has NADPH-dependent aldehyde reductase activity towards 2-carboxybenzaldehyde, 2-nitrobenzaldehyde and pyridine-2-aldehyde (in vitro) . Can reduce 1,2-naphthoquinone and 9,10-phenanthrenequinone (in vitro) . Can reduce the dialdehyde protein-binding form of aflatoxin B1 (AFB1) to the non-binding AFB1 dialcohol. May be involved in protection of liver against the toxic and carcinogenic effects of AFB1, a potent hepatocarcinogen.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Polyclonal Antibody

Applications

Western blot

Purification

Affinity purified against immunogen

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Format

Liquid

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Reconstitution

Store at -20C. Avoid repeated freeze/thaw cycles.

Molecular Weight

40kDa

Fragment

IgG

NCBI Gene Symbol

AKR7A2

Host or Source

Rabbit

Protein Name

Aflatoxin B1 aldehyde reductase member 2

Gene Name URL

AKR7A2

Nucleotide Accession Number

NM_003689.3

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