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PKM Antibody

Product Specifications

CAS Number

9007-83-4

Gene Name

Pyruvate kinase, muscle

Gene Aliases

PK3, TCB, p58, OIP3, PKM2, CTHBP, THBP1, HEL-S-30

Gene ID

5315

Swiss Prot

P14618

Accession Number

NP_001193725.1

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant Protein of human PKM2

Target

This gene encodes a protein involved in glycolysis. The encoded protein is a pyruvate kinase that catalyzes the transfer of a phosphoryl group from phosphoenolpyruvate to ADP, generating ATP and pyruvate. This protein has been shown to interact with thyroid hormone and may mediate cellular metabolic effects induced by thyroid hormones. This protein has been found to bind Opa protein, a bacterial outer membrane protein involved in gonococcal adherence to and invasion of human cells, suggesting a role of this protein in bacterial pathogenesis. Several alternatively spliced transcript variants encoding a few distinct isoforms have been reported.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Polyclonal Antibody

Applications

WB, IHC, IF, IP

Purification

Affinity purified against immunogen

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Format

Liquid

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Reconstitution

Store at -20C. Avoid repeated freeze/thaw cycles.

Molecular Weight

58 kDa

Fragment

IgG

NCBI Gene Symbol

PKM

Host or Source

Rabbit

Protein Name

Pyruvate kinase PKM

Gene Name URL

PKM

Nucleotide Accession Number

NM_001206796.2

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