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SLC27A2 Antibody

Product Specifications

CAS Number

9007-83-4

Gene Name

Solute carrier family 27 member 2

Gene Aliases

ACSVL1; arachidonate--CoA ligase; FACVL1; FATP2; FATP-2; fatty acid transport protein 2; fatty-acid-coenzyme A ligase, very long-chain 1; hFACVL1; HsT17226; long-chain-fatty-acid--CoA ligase; phytanate--CoA ligase; solute carrier family 27 (fatty acid transporter), member 2; THCA-CoA ligase; very long-chain acyl-CoA synthetase; very long-chain fatty-acid-coenzyme A ligase 1; very long-chain-fatty-acid-CoA ligase; VLACS; VLCS.

Gene ID

11001

Accession Number

https://www.ncbi.nlm.nih.gov/protein/NP_003636

Reactivity

Human, Mouse

Immunogen

SLC27A2 (NP_003636, 25 a.a. ~ 123 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Target

The protein encoded by this gene is an isozyme of long-chain fatty-acid-coenzyme A ligase family. Although differing in substrate specificity, subcellular localization, and tissue distribution, all isozymes of this family convert free long-chain fatty acids into fatty acyl-CoA esters, and thereby play a key role in lipid biosynthesis and fatty acid degradation. This isozyme activates long-chain, branched-chain and very-long-chain fatty acids containing 22 or more carbons to their CoA derivatives. It is expressed primarily in liver and kidney, and is present in both endoplasmic reticulum and peroxisomes, but not in mitochondria. Its decreased peroxisomal enzyme activity is in part responsible for the biochemical pathology in X-linked adrenoleukodystrophy. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq

Clonality

Monoclonal

Clone

1F1

Type

Monoclonal Antibody

Sequence

YFFQDIGYFLKVAAVGRRVRSYGQRRPARTILRAFLEKARQTPHKPFLLFRDETLTYAQVDRRSNQVARALHDHLGLRQGDCVALLMGNEPAYVWLWLG

Applications

Enzyme-linked immunosorbent assay|Immunofluorescence

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Format

Liquid

Reconstitution

Store at -20C or lower. Aliquot to avoid repeated freezing and thawing.

Fragment

IgG2a Kappa

NCBI Gene Symbol

SLC27A2

Host or Source

Mouse

Protein Name

Homo sapiens solute carrier family 27 member 2 (SLC27A2), transcript variant 1, mRNA|very long-chain acyl-CoA synthetase isoform 1 [Homo sapiens]

Gene Name URL

SLC27A2

Nucleotide Accession Number

https://www.ncbi.nlm.nih.gov/nuccore/NM_003645

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