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NPC2 Antibody

Product Specifications

CAS Number

9007-83-4

Gene Name

NPC intracellular cholesterol transporter 2

Gene Aliases

EDDM1; epididymal protein 1; epididymis secretory sperm binding protein; HE1; human epididymis-specific protein 1; Niemann-Pick disease type C2 protein; NPC intracellular cholesterol transporter 2; tissue-specific secretory protein.

Gene ID

10577

Accession Number

https://www.ncbi.nlm.nih.gov/protein/NP_006423.1

Reactivity

Human, Mouse

Immunogen

NPC2 (NP_006423.1, 52 a.a. ~ 151 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Target

This gene encodes a protein containing a lipid recognition domain. The encoded protein may function in regulating the transport of cholesterol through the late endosomal/lysosomal system. Mutations in this gene have been associated with Niemann-Pick disease, type C2 and frontal lobe atrophy. [provided by RefSeq

Clonality

Monoclonal

Clone

1F4

Type

Monoclonal Antibody

Sequence

GQSYSVNVTFTSNIQSKSSKAVVHGILMGVPVPFPIPEPDGCKSGINCPIQKDKTYSYLNKLPVKSEYPSIKLVVEWQLQDDKNQSLFCWEIPVQIVSHL

Applications

Enzyme-linked immunosorbent assay|Immunoprecipitation

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Format

Liquid

Reconstitution

Store at -20C or lower. Aliquot to avoid repeated freezing and thawing.

Fragment

IgG2b Kappa

NCBI Gene Symbol

NPC2

Host or Source

Mouse

Protein Name

Homo sapiens NPC intracellular cholesterol transporter 2 (NPC2), transcript variant 2, mRNA|NPC intracellular cholesterol transporter 2 precursor [Homo sapiens]

Gene Name URL

NPC2

Nucleotide Accession Number

https://www.ncbi.nlm.nih.gov/nuccore/NM_006432

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