PTGES Antibody
Product Specifications
CAS Number
9007-83-4
Gene Name
Prostaglandin E synthase
Gene Aliases
Glutathione peroxidase PTGES; glutathione S-transferase 1-like 1; glutathione transferase PTGES; MGST1L1; MGST1-L1; MGST1-like 1; MGST-IV; microsomal glutathione S-transferase 1-like 1; microsomal prostaglandin E synthase-1; MPGES; mPGES-1; p53-induced apoptosis protein 12; p53-induced gene 12 protein; PGES; PIG12; PP102; PP1294; prostaglandin E synthase; TP53I12; tumor protein p53 inducible protein 12.
Gene ID
9536
Accession Number
https://www.ncbi.nlm.nih.gov/protein/AAH08280.1
Reactivity
Human, Mouse
Immunogen
PTGES (AAH08280.1, 1 a.a. ~ 152 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Target
The protein encoded by this gene is a glutathione-dependent prostaglandin E synthase. The expression of this gene has been shown to be induced by proinflammatory cytokine interleukin 1 beta (IL1B) . Its expression can also be induced by tumor suppressor protein TP53, and may be involved in TP53 induced apoptosis. Knockout studies in mice suggest that this gene may contribute to the pathogenesis of collagen-induced arthritis and mediate acute pain during inflammatory responses. [provided by RefSeq
Clonality
Monoclonal
Clone
2B9
Type
Monoclonal Antibody
Sequence
MPAHSLVMSSPALPAFLLCSTLLVIKMYVVAIITGQVRLRKKAFANPEDALRHGGPQYCRSDPDVERCLRAHRNDMETIYPFLFLGFVYSFLGPNPFVAWMHFLVFLVGRVAHTVAYLGKLRAPIRSVTYTLAQLPCASMALQILWEAARHL
Applications
Enzyme-linked immunosorbent assay|Immunoprecipitation
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions
Reconstitution & Storage Instructions
Western Blotting/Immunoblotting (WB/IB) Protocol
Western Blotting/Immunoblotting (WB/IB) Protocol
Immunohistochemistry (IHC) Protocol
Immunohistochemistry (IHC) Protocol
Immunocytochemistry (ICC) Protocol
Immunocytochemistry (ICC) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Blocking Peptide Competition Protocol (BPCP)
Blocking Peptide Competition Protocol (BPCP)
Immunoprecipitation (IP) Protocol
Immunoprecipitation (IP) Protocol
Antibody Array (AA) Protocol
Antibody Array (AA) Protocol
Format
Liquid
Reconstitution
Store at -20C or lower. Aliquot to avoid repeated freezing and thawing.
Fragment
IgG2b Kappa
NCBI Gene Symbol
PTGES
Host or Source
Mouse
Protein Name
Homo sapiens prostaglandin E synthase, mRNA (cDNA clone MGC:10317 IMAGE:3623516), complete cds|Prostaglandin E synthase [Homo sapiens]
Gene Name URL
PTGES
Nucleotide Accession Number
https://www.ncbi.nlm.nih.gov/nuccore/BC008280
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