ST14 Antibody
Product Specifications
CAS Number
9007-83-4
Gene Name
ST14 transmembrane serine protease matriptase
Gene Aliases
ARCI11; CAP3; channel-activating protein 3; HAI; membrane-type serine protease 1; MTSP1; MT-SP1; prostamin; PRSS14; serine protease 14; serine protease TADG-15; SNC19; suppression of tumorigenicity 14 (colon carcinoma) ; suppression of tumorigenicity 14 (colon carcinoma, matriptase, epithin) ; suppressor of tumorigenicity 14 protein; TADG15; TMPRSS14; tumor associated differentially expressed gene 15 protein.
Gene ID
6768
Accession Number
https://www.ncbi.nlm.nih.gov/protein/NP_068813
Reactivity
Human, Mouse
Immunogen
ST14 (NP_068813, 298 a.a. ~ 400 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Target
The protein encoded by this gene is an epithelial-derived, integral membrane serine protease. This protease forms a complex with the Kunitz-type serine protease inhibitor, HAI-1, and is found to be activated by sphingosine 1-phosphate. This protease has been shown to cleave and activate hepatocyte growth factor/scattering factor, and urokinase plasminogen activator, which suggest the function of this protease as an epithelial membrane activator for other proteases and latent growth factors. The expression of this protease has been associated with breast, colon, prostate, and ovarian tumors, which implicates its role in cancer invasion, and metastasis. [provided by RefSeq
Clonality
Monoclonal
Clone
2F4
Type
Monoclonal Antibody
Sequence
PPSYNLTFHSSQNVLLITLITNTERRHPGFEATFFQLPRMSSCGGRLRKAQGTFNSPYYPGHYPPNIDCTWNIEVPNNQHVKVRFKFFYLLEPGVPAGTCPKD
Applications
Enzyme-linked immunosorbent assay
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions
Reconstitution & Storage Instructions
Western Blotting/Immunoblotting (WB/IB) Protocol
Western Blotting/Immunoblotting (WB/IB) Protocol
Immunohistochemistry (IHC) Protocol
Immunohistochemistry (IHC) Protocol
Immunocytochemistry (ICC) Protocol
Immunocytochemistry (ICC) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Blocking Peptide Competition Protocol (BPCP)
Blocking Peptide Competition Protocol (BPCP)
Immunoprecipitation (IP) Protocol
Immunoprecipitation (IP) Protocol
Antibody Array (AA) Protocol
Antibody Array (AA) Protocol
Format
Liquid
Reconstitution
Store at -20C or lower. Aliquot to avoid repeated freezing and thawing.
Fragment
IgG2a Kappa
NCBI Gene Symbol
ST14
Host or Source
Mouse
Protein Name
Homo sapiens suppression of tumorigenicity 14 (ST14), mRNA|suppressor of tumorigenicity 14 protein [Homo sapiens]
Gene Name URL
ST14
Nucleotide Accession Number
https://www.ncbi.nlm.nih.gov/nuccore/NM_021978
Curated Selection
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