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AKR1D1 Antibody

Product Specifications

CAS Number

9007-83-4

Gene Name

Aldo-keto reductase family 1 member D1

Gene Aliases

3o5bred; aldo-keto reductase family 1 member D1; CBAS2; delta (4) -3-ketosteroid 5-beta-reductase; delta (4) -3-oxosteroid 5-beta-reductase; SRD5B1; steroid-5-beta-reductase, beta polypeptide 1 (3-oxo-5 beta-steroid delta 4-dehydrogenase beta 1) .

Gene ID

6718

Accession Number

https://www.ncbi.nlm.nih.gov/protein/NP_005980

Reactivity

Human, Mouse

Immunogen

AKR1D1 (NP_005980, 227 a.a. ~ 326 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Target

The enzyme encoded by this gene is responsible for the catalysis of the 5-beta-reduction of bile acid intermediates and steroid hormones carrying a delta (4) -3-one structure. Deficiency of this enzyme may contribute to hepatic dysfunction. [provided by RefSeq

Clonality

Monoclonal

Clone

1C2

Type

Monoclonal Antibody

Sequence

NPIWVNVSSPPLLKDALLNSLGKRYNKTAAQIVLRFNIQRGVVVIPKSFNLERIKENFQIFDFSLTEEEMKDIEALNKNVRFVELLMWRDHPEYPFHDEY

Applications

Enzyme-linked immunosorbent assay|Western blot

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Format

Liquid

Reconstitution

Store at -20C or lower. Aliquot to avoid repeated freezing and thawing.

Fragment

IgG2b Kappa

NCBI Gene Symbol

AKR1D1

Host or Source

Mouse

Protein Name

3-oxo-5-beta-steroid 4-dehydrogenase isoform 1 [Homo sapiens]|Homo sapiens aldo-keto reductase family 1 member D1 (AKR1D1), transcript variant 1, mRNA

Gene Name URL

AKR1D1

Nucleotide Accession Number

https://www.ncbi.nlm.nih.gov/nuccore/NM_005989

Frequently Asked Questions

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