NTRK3 Antibody
Product Specifications
CAS Number
9007-83-4
Gene Name
Neurotrophic receptor tyrosine kinase 3
Gene Aliases
ETS related protein-neurotrophic receptor tyrosine kinase fusion protein; ETV6-NTRK3 fusion; gp145 (trkC) ; GP145-TrkC; neurotrophic tyrosine kinase, receptor, type 3; NT-3 growth factor receptor; TRKC; tyrosine kinase receptor C.
Gene ID
4916
Accession Number
https://www.ncbi.nlm.nih.gov/protein/AAH13693
Reactivity
Human, Mouse
Immunogen
NTRK3 (AAH13693, 41 a.a. ~ 160 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Target
This gene encodes a member of the neurotrophic tyrosine receptor kinase (NTRK) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. Signalling through this kinase leads to cell differentiation and may play a role in the development of proprioceptive neurons that sense body position. Mutations in this gene have been associated with medulloblastomas, secretory breast carcinomas and other cancers. [provided by RefSeq
Clonality
Monoclonal
Clone
4D5
Type
Monoclonal Antibody
Sequence
TEINCRRPDDGNLFPLLEGQDSGNSNGNASINITDISRNITSIHIENWRSLHTLNAVDMELYTGLQKLTIKNSGLRSIQPRAFAKNPHLRYINLSSNRLTTLSWQLFQTLSLRELQLEQN
Applications
Enzyme-linked immunosorbent assay|Immunofluorescence
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions
Reconstitution & Storage Instructions
Western Blotting/Immunoblotting (WB/IB) Protocol
Western Blotting/Immunoblotting (WB/IB) Protocol
Immunohistochemistry (IHC) Protocol
Immunohistochemistry (IHC) Protocol
Immunocytochemistry (ICC) Protocol
Immunocytochemistry (ICC) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Blocking Peptide Competition Protocol (BPCP)
Blocking Peptide Competition Protocol (BPCP)
Immunoprecipitation (IP) Protocol
Immunoprecipitation (IP) Protocol
Antibody Array (AA) Protocol
Antibody Array (AA) Protocol
Format
Liquid
Reconstitution
Store at -20C or lower. Aliquot to avoid repeated freezing and thawing.
Fragment
IgG2a Kappa
NCBI Gene Symbol
NTRK3
Host or Source
Mouse
Protein Name
Homo sapiens neurotrophic tyrosine kinase, receptor, type 3, mRNA (cDNA clone MGC:17113 IMAGE:4181574), complete cds|Neurotrophic tyrosine kinase, receptor, type 3 [Homo sapiens]
Gene Name URL
NTRK3
Nucleotide Accession Number
https://www.ncbi.nlm.nih.gov/nuccore/BC013693
Curated Selection
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