GUCY2D Antibody
Product Specifications
CAS Number
9007-83-4
Gene Name
Guanylate cyclase 2D, retinal
Gene Aliases
CACD1; CG-E; cone rod dystrophy 6; CORD5; CORD6; CSNB1I; CYGD; guanylate cyclase 2D, membrane (retina-specific) ; GUC1A4; GUC2D; LCA; LCA1; RCD2; retGC; RETGC-1; retinal guanylate cyclase 1; retinal guanylyl cyclase 1; rod outer segment membrane guanylate cyclase; ROSGC; ROS-GC; ROS-GC1.
Gene ID
3000
Accession Number
https://www.ncbi.nlm.nih.gov/protein/NP_000171
Reactivity
Human, Mouse
Immunogen
GUCY2D (NP_000171, 521 a.a. ~ 630 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Target
This gene encodes a retina-specific guanylate cyclase, which is a member of the membrane guanylyl cyclase family. Like other membrane guanylyl cyclases, this enzyme has a hydrophobic amino-terminal signal sequence followed by a large extracellular domain, a single membrane spanning domain, a kinase homology domain, and a guanylyl cyclase catalytic domain. In contrast to other membrane guanylyl cyclases, this enzyme is not activated by natriuretic peptides. Mutations in this gene result in Leber congenital amaurosis and cone-rod dystrophy-6 diseases. [provided by RefSeq
Clonality
Monoclonal
Clone
1000000
Type
Monoclonal Antibody
Sequence
RKVAQGSRSSLGARSMSDIRSGPSQHLDSPNIGVYEGDRVWLKKFPGDQHIAIRPATKTAFSKLQELRHENVALYLGLFLARGAEGPAALWEGNLAVVSEHCTRGSLQDL
Applications
Enzyme-linked immunosorbent assay|Immunofluorescence|Western blot
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions
Reconstitution & Storage Instructions
Western Blotting/Immunoblotting (WB/IB) Protocol
Western Blotting/Immunoblotting (WB/IB) Protocol
Immunohistochemistry (IHC) Protocol
Immunohistochemistry (IHC) Protocol
Immunocytochemistry (ICC) Protocol
Immunocytochemistry (ICC) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Blocking Peptide Competition Protocol (BPCP)
Blocking Peptide Competition Protocol (BPCP)
Immunoprecipitation (IP) Protocol
Immunoprecipitation (IP) Protocol
Antibody Array (AA) Protocol
Antibody Array (AA) Protocol
Format
Liquid
Reconstitution
Store at -20C or lower. Aliquot to avoid repeated freezing and thawing.
Fragment
IgG
NCBI Gene Symbol
GUCY2D
Host or Source
Mouse
Protein Name
Homo sapiens guanylate cyclase 2D, retinal (GUCY2D), mRNA|retinal guanylyl cyclase 1 [Homo sapiens]
Gene Name URL
GUCY2D
Nucleotide Accession Number
https://www.ncbi.nlm.nih.gov/nuccore/NM_000180
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