FDPS Antibody
Product Specifications
CAS Number
9007-83-4
Gene Name
Farnesyl diphosphate synthase
Gene Aliases
(2E,6E) -farnesyl diphosphate synthase; farnesyl pyrophosphate synthase; farnesyl pyrophosphate synthetase, dimethylallyltranstransferase, geranyltranstransferase; FPP synthase; FPP synthetase; FPPS; FPS; POROK9.
Gene ID
2224
Accession Number
https://www.ncbi.nlm.nih.gov/protein/NP_001995.1
Reactivity
Human, Mouse
Immunogen
FDPS (NP_001995.1, 320 a.a. ~ 419 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Target
This gene encodes an enzyme that catalyzes the production of geranyl pyrophosphate and farnesyl pyrophosphate from isopentenyl pyrophosphate and dimethylallyl pyrophosphate. The resulting product, farnesyl pyrophosphate, is a key intermediate in cholesterol and sterol biosynthesis, a substrate for protein farnesylation and geranylgeranylation, and a ligand or agonist for certain hormone receptors and growth receptors. Drugs that inhibit this enzyme prevent the post-translational modifications of small GTPases and have been used to treat diseases related to bone resorption. Multiple pseudogenes have been found on chromosomes 1, 7, 14, 15, 21 and X. Multiple transcript variants encoding different isoforms have been found for this gene
Clonality
Monoclonal
Clone
3A6
Type
Monoclonal Antibody
Sequence
VTGKIGTDIQDNKCSWLVVQCLQRATPEQYQILKENYGQKEAEKVARVKALYEELDLPAVFLQYEEDSYSHIMALIEQYAAPLPPAVFLGLARKIYKRRK
Applications
Enzyme-linked immunosorbent assay
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions
Reconstitution & Storage Instructions
Western Blotting/Immunoblotting (WB/IB) Protocol
Western Blotting/Immunoblotting (WB/IB) Protocol
Immunohistochemistry (IHC) Protocol
Immunohistochemistry (IHC) Protocol
Immunocytochemistry (ICC) Protocol
Immunocytochemistry (ICC) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Blocking Peptide Competition Protocol (BPCP)
Blocking Peptide Competition Protocol (BPCP)
Immunoprecipitation (IP) Protocol
Immunoprecipitation (IP) Protocol
Antibody Array (AA) Protocol
Antibody Array (AA) Protocol
Format
Liquid
Reconstitution
Store at -20C or lower. Aliquot to avoid repeated freezing and thawing.
Fragment
IgG2a Kappa
NCBI Gene Symbol
FDPS
Host or Source
Mouse
Protein Name
Farnesyl pyrophosphate synthase isoform a [Homo sapiens]|Homo sapiens farnesyl diphosphate synthase (FDPS), transcript variant 1, mRNA
Gene Name URL
FDPS
Nucleotide Accession Number
https://www.ncbi.nlm.nih.gov/nuccore/NM_002004
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
SGC63813-01 50 mg
1- (2-Aminoethyl) piperidine-4-carboxylic acid dihydrochloride
Sign In for Pricing
View Details SGC63813-02 0.5 g
1- (2-Aminoethyl) piperidine-4-carboxylic acid dihydrochloride
Sign In for Pricing
View Details 
MBS6453002-01 0.1 mL
Noggin (Synostoses (Multiple) Syndrome 1, SYNS 1, NOG, SYNS1, SYM1, Symphalangism 1 (Proximal), SYM 1) (MaxLight 650)
Sign In for Pricing
View Details