APOBEC3A Antibody
Product Specifications
CAS Number
9007-83-4
Gene Aliases
A3A, APOBEC3A
Gene ID
100913187; 200315
Swiss Prot
P31941
Accession Number
NP_001180218
Reactivity
Human, Mouse
Immunogen
A synthesized peptide derived from human APOBEC3A, corresponding to a region with the internal amino acids.
Target
DNA deaminase (cytidine deaminase) with restriction activity against viruses, foreign DNA and mobility of retrotransposons. Exhibits antiviral activity against adeno-associated virus (AAV) and human T-cell leukemia virus type 1 (HTLV-1) and may inhibit the mobility of LTR and non-LTR retrotransposons. Selectively targets single-stranded DNA and can deaminate both methylcytosine and cytosine in foreign DNA. Can induce somatic hypermutation in the nuclear and mitochondrial DNA. May also play a role in the epigenetic regulation of gene expression through the process of active DNA demethylation.1
Clonality
Polyclonal
Type
Polyclonal Antibody
Applications
WB, IF, ICC
Purification
Peptide affinity chromatography
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions
Reconstitution & Storage Instructions
Western Blotting/Immunoblotting (WB/IB) Protocol
Western Blotting/Immunoblotting (WB/IB) Protocol
Immunohistochemistry (IHC) Protocol
Immunohistochemistry (IHC) Protocol
Immunocytochemistry (ICC) Protocol
Immunocytochemistry (ICC) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Blocking Peptide Competition Protocol (BPCP)
Blocking Peptide Competition Protocol (BPCP)
Immunoprecipitation (IP) Protocol
Immunoprecipitation (IP) Protocol
Antibody Array (AA) Protocol
Antibody Array (AA) Protocol
Concentration
1 mg/mL
Format
Liquid// PBS (pH 7.4), 150mM NaCl, 0.02% sodium azide and 50% glycerol
Reconstitution
Store at -20° C. Stable for 12 months from date of receipt.
Molecular Weight
26 kDa
Fragment
IgG
Specificity
APOBEC3A Ab detects endogenous levels of total APOBEC3A.
NCBI Gene Symbol
APOBEC3A
Host or Source
Rabbit
Protein Name
DNA dC->dU-editing enzyme APOBEC-3A
Gene Name URL
APOBEC3A
Nucleotide Accession Number
NM_001193289
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