MLKL Antibody
Product Specifications
CAS Number
9007-83-4
Gene Aliases
HMLKL
Gene ID
197259
Swiss Prot
Q8NB16
Accession Number
NP_001135969
Reactivity
Human, Mouse, Rat
Immunogen
A synthesized peptide derived from human MLKL.
Target
Pseudokinase that plays a key role in TNF-induced necroptosis, a programmed cell death process. Activated following phosphorylation by RIPK3, leading to homotrimerization, localization to the plasma membrane and execution of programmed necrosis characterized by calcium influx and plasma membrane damage. Does not have protein kinase activity.
Clonality
Polyclonal
Type
Polyclonal Antibody
Applications
WB, IHC, IF, ICC
Purification
The antiserum was purified by peptide affinity chromatography
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions
Reconstitution & Storage Instructions
Western Blotting/Immunoblotting (WB/IB) Protocol
Western Blotting/Immunoblotting (WB/IB) Protocol
Immunohistochemistry (IHC) Protocol
Immunohistochemistry (IHC) Protocol
Immunocytochemistry (ICC) Protocol
Immunocytochemistry (ICC) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Blocking Peptide Competition Protocol (BPCP)
Blocking Peptide Competition Protocol (BPCP)
Immunoprecipitation (IP) Protocol
Immunoprecipitation (IP) Protocol
Antibody Array (AA) Protocol
Antibody Array (AA) Protocol
Concentration
1 mg/mL
Format
Liquid.// PBS pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Reconstitution
Store at -20° C. Stable for 12 months from date of receipt._x005F
Molecular Weight
54 kDa
Fragment
IgG
Specificity
MLKL Ab detects endogenous levels of total MLKL.
NCBI Gene Symbol
MLKL
Host or Source
Rabbit
Protein Name
Mixed lineage kinase domain-like protein
Gene Name URL
MLKL
Nucleotide Accession Number
NM_001142497
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