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GCLM Antibody

Product Specifications

CAS Number

9007-83-4

Gene Aliases

GLCLR

Gene ID

2730

Swiss Prot

P48507

Accession Number

NP_001295182

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant protein of human GCLM

Target

Glutamate-cysteine ligase, also known as gamma-glutamylcysteine synthetase, is the first rate limiting enzyme of glutathione synthesis. The enzyme consists of two subunits, a heavy catalytic subunit and a light regulatory subunit. Gamma glutamylcysteine synthetase deficiency has been implicated in some forms of hemolytic anemia. Alternative splicing results in multiple transcript variants encoding different isoforms.

Clonality

Polyclonal

Type

Polyclonal Antibody

Applications

WB, IHC

Purification

Immunogen affinity chromatography

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

1 mg/mL

Format

Liquid

Reconstitution

Store at +4C. For long term storage, aliquot and store at -20C. Avoid freeze/thaw cycles.

Molecular Weight

30 kDa

NCBI Gene Symbol

GCLM

Host or Source

Rabbit

Protein Name

Glutamate--cysteine ligase regulatory subunit

Gene Name URL

GCLM

Nucleotide Accession Number

NM_001308253

Frequently Asked Questions

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